Igelmann, Sebastian

Metformin inhibits the senescence‐associated secretory phenotype by interfering with IKK/NF‐κ B activation

Moiseeva, O., Deschênes‐Simard, X., St‐Germain, E., Igelmann, S., Huot, G., Cadar, A. E., Bourdeau, V., Pollak, M. N., & Ferbeyre, G. (2013) · Aging Cell

Metabolism, Diabetes, and CancerNF-κB Signaling Pathways

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Tumor suppressor activity of the ERK/MAPK pathway by promoting selective protein degradation

Deschênes-Simard, X., Gaumont-Leclerc, M.-F., Bourdeau, V., Lessard, F., Moiseeva, O., Forest, V., Igelmann, S., Mallette, F. A., Saba-El-Leil, M. K., Meloche, S., et al. (2013) · Genes & Development

Telomeres, Telomerase, and SenescenceMelanoma and MAPK Pathways

Cited by 194

Senescence-associated ribosome biogenesis defects contributes to cell cycle arrest through the Rb pathway

Lessard, F., Igelmann, S., Trahan, C., Huot, G., Saint-Germain, E., Mignacca, L., Del Toro, N., Lopes-Paciencia, S., Le Calvé, B., Montero, M., et al. (2018) · Nature Cell Biology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 174

A hydride transfer complex reprograms NAD metabolism and bypasses senescence

Igelmann, S., Lessard, F., Uchenunu, O., Bouchard, J., Fernandez-Ruiz, A., Rowell, M.-C., Lopes-Paciencia, S., Papadopoli, D., Fouillen, A., Ponce, K. J., et al. (2021) · Molecular Cell

Telomeres, Telomerase, and SenescenceSirtuins and Resveratrol in Medicine

Cited by 60

Circumventing senescence is associated with stem cell properties and metformin sensitivity

Deschênes‐Simard, X., Parisotto, M., Rowell, M., Le Calvé, B., Igelmann, S., Moineau‐Vallée, K., Saint‐Germain, E., Kalegari, P., Bourdeau, V., Kottakis, F., et al. (2019) · Aging Cell

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 45

Mitochondrial ETF insufficiency drives neoplastic growth by selectively optimizing cancer bioenergetics

Papadopoli, D., Palia, R., Jovanovic, P., Tabariès, S., Ciccolini, E., Sabourin, V., Igelmann, S., McLaughlan, S., Zhan, L., Kim, H., et al. (2026) · eLife

Cancer, Hypoxia, and MetabolismCancer, Lipids, and Metabolism

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