Affourtit, Charles

Mitochondrial superoxide: production, biological effects, and activation of uncoupling proteins

Brand, M. D., Affourtit, C., Esteves, T. C., Green, K., Lambert, A. J., Miwa, S., Pakay, J. L., & Parker, N. (2004) · Free Radical Biology and Medicine

Mitochondrial Function and PathologyRedox biology and oxidative stress

Cited by 1,032

Uncoupling protein-2 contributes significantly to high mitochondrial proton leak in INS-1E insulinoma cells and attenuates glucose-stimulated insulin secretion

Affourtit, C., & Brand, M. D. (2008) · Biochemical Journal

Pancreatic function and diabetesMitochondrial Function and Pathology

Cited by 85

Uncoupling protein-2 attenuates glucose-stimulated insulin secretion in INS-1E insulinoma cells by lowering mitochondrial reactive oxygen species

Affourtit, C., Jastroch, M., & Brand, M. D. (2011) · Free Radical Biology and Medicine

Pancreatic function and diabetesMitochondrial Function and Pathology

Cited by 83

On the role of uncoupling protein-2 in pancreatic beta cells

Affourtit, C., & Brand, M. D. (2008) · Biochimica et Biophysica Acta (BBA) - Bioenergetics

Pancreatic function and diabetesMitochondrial Function and Pathology

Cited by 78

Stronger control of ATP/ADP by proton leak in pancreatic β-cells than skeletal muscle mitochondria

Affourtit, C., & Brand, M. D. (2006) · Biochemical Journal

Mitochondrial Function and PathologyPancreatic function and diabetes

Cited by 71

Mitochondrial involvement in skeletal muscle insulin resistance: A case of imbalanced bioenergetics

Affourtit, C. (2016) · Biochimica et Biophysica Acta (BBA) - Bioenergetics

Mitochondrial Function and PathologyMetabolism, Diabetes, and Cancer

Cited by 67

On the mechanism by which dietary nitrate improves human skeletal muscle function

Affourtit, C., Bailey, S. J., Jones, A. M., Smallwood, M. J., & Winyard, P. G. (2015) · Frontiers in Physiology

Cardiovascular and exercise physiologyNitric Oxide and Endothelin Effects

Cited by 58

Novel insights into pancreatic β-cell glucolipotoxicity from real-time functional analysis of mitochondrial energy metabolism in INS-1E insulinoma cells

Barlow, J., & Affourtit, C. (2013) · Biochemical Journal

Pancreatic function and diabetesMitochondrial Function and Pathology

Cited by 53

Palmitate-induced impairment of glucose-stimulated insulin secretion precedes mitochondrial dysfunction in mouse pancreatic islets

Barlow, J., Jensen, V. H., Jastroch, M., & Affourtit, C. (2016) · Biochemical Journal

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 45

Mitochondrial uncoupling protein-2 is not involved in palmitate-induced impairment of glucose-stimulated insulin secretion in INS-1E insulinoma cells and is not needed for the amplification of insulin release

Hirschberg Jensen, V., & Affourtit, C. (2015) · Biochemistry and Biophysics Reports

Pancreatic function and diabetesMitochondrial Function and Pathology

Cited by 9