Lippmann, Ethan S.

Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells

Lippmann, E. S., Azarin, S. M., Kay, J. E., Nessler, R. A., Wilson, H. K., Al-Ahmad, A., Palecek, S. P., & Shusta, E. V. (2012) · Nature Biotechnology

Barrier Structure and Function StudiesPluripotent Stem Cells Research

Cited by 800

A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources

Lippmann, E. S., Al-Ahmad, A., Azarin, S. M., Palecek, S. P., & Shusta, E. V. (2014) · Scientific Reports

Barrier Structure and Function StudiesDrug Transport and Resistance Mechanisms

Cited by 508

Reactive astrocytes transduce inflammation in a blood-brain barrier model through a TNF-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin

Kim, H., Leng, K., Park, J., Sorets, A. G., Kim, S., Shostak, A., Embalabala, R. J., Mlouk, K., Katdare, K. A., Rose, I. V. L., et al. (2022) · Nature Communications

Barrier Structure and Function StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 201

Accelerated differentiation of human induced pluripotent stem cells to blood–brain barrier endothelial cells

Hollmann, E. K., Bailey, A. K., Potharazu, A. V., Neely, M. D., Bowman, A. B., & Lippmann, E. S. (2017) · Fluids and Barriers of the CNS

Barrier Structure and Function StudiesPluripotent Stem Cells Research

Cited by 189

iPSC-Derived Brain Endothelium Exhibits Stable, Long-Term Barrier Function in Perfused Hydrogel Scaffolds

Faley, S. L., Neal, E. H., Wang, J. X., Bosworth, A. M., Weber, C. M., Balotin, K. M., Lippmann, E. S., & Bellan, L. M. (2019) · Stem Cell Reports

Barrier Structure and Function Studies3D Printing in Biomedical Research

Cited by 106

Elucidating brain transport pathways and cell type-dependent gene silencing of a durable lipid–siRNA conjugate administered into cerebrospinal fluid

Sorets, A. G., Schwensen, K. R., Francini, N., Kjar, A., Abdulrahman, A. M., Shostak, A., Katdare, K. A., Schoch, K. M., Cowell, R. P., Park, J. C., et al. (2025) · Nucleic Acids Research

RNA Interference and Gene DeliveryBarrier Structure and Function Studies

Cited by 6

Lipid-siRNA conjugate accesses a perivascular transport mechanism and achieves widespread and durable knockdown in the central nervous system

Sorets, A., Schwensen, K., Francini, N., Kjar, A., Abdulrahman, A., Shostak, A., Katdare, K., Schoch, K., Cowell, R., Park, J., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory)

RNA Interference and Gene DeliveryBarrier Structure and Function Studies

Cited by 4