McDonald, Oliver G.

Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis

McDonald, O. G., Li, X., Saunders, T., Tryggvadottir, R., Mentch, S. J., Warmoes, M. O., Word, A. E., Carrer, A., Salz, T. H., Natsume, S., et al. (2017) · Nature Genetics

Epigenetics and DNA MethylationPancreatic and Hepatic Oncology Research

Cited by 494

Three-dimensional culture system identifies a new mode of cetuximab resistance and disease-relevant genes in colorectal cancer

Li, C., Singh, B., Graves-Deal, R., Ma, H., Starchenko, A., Fry, W. H., Lu, Y., Wang, Y., Bogatcheva, G., Khan, M. P., et al. (2017) · Proceedings of the National Academy of Sciences

Colorectal Cancer Treatments and StudiesCancer Cells and Metastasis

Cited by 47

Pentose conversions support the tumorigenesis of pancreatic cancer distant metastases

Bechard, M. E., Word, A. E., Tran, A. V., Liu, X., Locasale, J. W., & McDonald, O. G. (2018) · Oncogene

Cancer, Hypoxia, and MetabolismPancreatic and Hepatic Oncology Research

Cited by 35

Pancreatic cancers suppress negative feedback of glucose transport to reprogram chromatin for metastasis

Bechard, M. E., Smalling, R., Hayashi, A., Zhong, Y., Word, A. E., Campbell, S. L., Tran, A. V., Weiss, V. L., Iacobuzio-Donahue, C., Wellen, K. E., et al. (2020) · Nature Communications

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 33