Spyridopoulos, Ioakim

Mitochondrial telomerase reverse transcriptase binds to and protects mitochondrial DNA and function from damage

Haendeler, J., Dröse, S., Büchner, N., Jakob, S., Altschmied, J., Goy, C., Spyridopoulos, I., Zeiher, A. M., Brandt, U., & Dimmeler, S. (2009) · Arteriosclerosis Thrombosis and Vascular Biology

Telomeres, Telomerase, and SenescenceMitochondrial Function and Pathology

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Pharmacological clearance of senescent cells improves survival and recovery in aged mice following acute myocardial infarction

Walaszczyk, A., Dookun, E., Redgrave, R., Tual‐Chalot, S., Victorelli, S., Spyridopoulos, I., Owens, A., Arthur, H. M., Passos, J. F., & Richardson, G. D. (2019) · Aging Cell

Telomeres, Telomerase, and SenescenceCardiac Fibrosis and Remodeling

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Clearance of senescent cells during cardiac ischemia–reperfusion injury improves recovery

Dookun, E., Walaszczyk, A., Redgrave, R., Palmowski, P., Tual‐Chalot, S., Suwana, A., Chapman, J., Jirkovsky, E., Donastorg Sosa, L., Gill, E., et al. (2020) · Aging Cell

Cardiac Ischemia and ReperfusionTelomeres, Telomerase, and Senescence

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CMV seropositivity and T‐cell senescence predict increased cardiovascular mortality in octogenarians: results from the Newcastle 85+ study

Spyridopoulos, I., Martin‐Ruiz, C., Hilkens, C., Yadegarfar, M. E., Isaacs, J., Jagger, C., Kirkwood, T., & von Zglinicki, T. (2016) · Aging Cell

Cytomegalovirus and herpesvirus researchTelomeres, Telomerase, and Senescence

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Roadmap for alleviating the manifestations of ageing in the cardiovascular system

Liberale, L., Tual-Chalot, S., Sedej, S., Ministrini, S., Georgiopoulos, G., Grunewald, M., Bäck, M., Bochaton-Piallat, M.-L., Boon, R. A., Ramos, G. C., et al. (2025) · Nature Reviews Cardiology

Cardiovascular Health and Disease PreventionTelomeres, Telomerase, and Senescence

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Atorvastatin induces T cell proliferation by a telomerase reverse transcriptase (TERT) mediated mechanism

Bennaceur, K., Atwill, M., Al Zhrany, N., Hoffmann, J., Keavney, B., Breault, D., Richardson, G., von Zglinicki, T., Saretzki, G., & Spyridopoulos, I. (2014) · Atherosclerosis

Telomeres, Telomerase, and SenescenceAtherosclerosis and Cardiovascular Diseases

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Terminally Differentiated CD4+ T Cells Promote Myocardial Inflammaging

Delgobo, M., Heinrichs, M., Hapke, N., Ashour, D., Appel, M., Srivastava, M., Heckel, T., Spyridopoulos, I., Hofmann, U., Frantz, S., et al. (2021) · Frontiers in Immunology

Cardiac Fibrosis and RemodelingAtherosclerosis and Cardiovascular Diseases

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