Samulski, R. Jude

Production of High-Titer Recombinant Adeno-Associated Virus Vectors in the Absence of Helper Adenovirus

Xiao, X., Li, J., & Samulski, R. J. (1998) · Journal of Virology

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 1,381

Engineering adeno-associated virus vectors for gene therapy

Li, C., & Samulski, R. J. (2020) · Nature Reviews Genetics

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 1,175

Cross-Packaging of a Single Adeno-Associated Virus (AAV) Type 2 Vector Genome into Multiple AAV Serotypes Enables Transduction with Broad Specificity

Rabinowitz, J. E., Rolling, F., Li, C., Conrath, H., Xiao, W., Xiao, X., & Samulski, R. J. (2002) · Journal of Virology

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 762

Adeno-associated virus terminal repeat (TR) mutant generates self-complementary vectors to overcome the rate-limiting step to transduction in vivo

McCarty, D. M., Fu, H., Monahan, P. E., Toulson, C. E., Naik, P., & Samulski, R. J. (2003) · Gene Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 547

Infectious entry pathway of adeno-associated virus and adeno-associated virus vectors

Bartlett, J. S., Wilcher, R., & Samulski, R. J. (2000) · Journal of Virology

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 532

Preclinical differences of intravascular AAV9 delivery to neurons and glia: a comparative study of adult mice and nonhuman primates

Gray, S. J., Matagne, V., Bachaboina, L., Yadav, S., Ojeda, S. R., & Samulski, R. J. (2011) · Molecular Therapy

Virus-based gene therapy researchBarrier Structure and Function Studies

Cited by 501

Cloning of adeno-associated virus into pBR322: Rescue of intact virus from the recombinant plasmid in human cells

Samulski, R. J., Berns, K. I., Tan, M., & Muzyczka, N. (1982) · Proceedings of the National Academy of Sciences

Virus-based gene therapy researchParvovirus B19 Infection Studies

Cited by 466

Integration of Adeno-Associated Virus (AAV) and Recombinant AAV Vectors

McCarty, D. M., Young, S. M., & Samulski, R. J. (2004) · Annual Review of Genetics

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 450

Optimizing promoters for recombinant adeno-associated virus-mediated gene expression in the peripheral and central nervous system using self-complementary vectors

Gray, S. J., Foti, S. B., Schwartz, J. W., Bachaboina, L., Taylor-Blake, B., Coleman, J., Ehlers, M. D., Zylka, M. J., McCown, T. J., & Samulski, R. J. (2011) · Human Gene Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 420

Packaging Capacity of Adeno-Associated Virus Serotypes: Impact of Larger Genomes on Infectivity and Postentry Steps

Grieger, J. C., & Samulski, R. J. (2005) · Journal of Virology

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 419

Phase 1 Gene Therapy for Duchenne Muscular Dystrophy Using a Translational Optimized AAV Vector

Bowles, D. E., McPhee, S. W., Li, C., Gray, S. J., Samulski, J. J., Camp, A. S., Li, J., Wang, B., Monahan, P. E., Rabinowitz, J. E., et al. (2012) · Molecular Therapy

Virus-based gene therapy researchNeurogenetic and Muscular Disorders Research

Cited by 400

Several log increase in therapeutic transgene delivery by distinct adeno-associated viral serotype vectors

Chao, H., Liu, Y., Rabinowitz, J., Li, C., Samulski, R. J., & Walsh, C. E. (2000) · Molecular Therapy

Virus-based gene therapy researchHemophilia Treatment and Research

Cited by 366

Long-term follow-up after gene therapy for canavan disease

Leone, P., Shera, D., McPhee, S. W. J., Francis, J. S., Kolodny, E. H., Bilaniuk, L. T., Wang, D.-J., Assadi, M., Goldfarb, O., Goldman, H. W., et al. (2012) · Science Translational Medicine

Virus-based gene therapy researchLysosomal Storage Disorders Research

Cited by 307

Rescue of adeno-associated virus from recombinant plasmids: Gene correction within the terminal repeats of AAV

Samulski, R. J., Srivastava, A., Berns, K. I., & Muzyczka, N. (1983) · Cell

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 297

Engineering and Selection of Shuffled AAV Genomes: A New Strategy for Producing Targeted Biological Nanoparticles

Li, W., Asokan, A., Wu, Z., Van Dyke, T., DiPrimio, N., Johnson, J. S., Govindaswamy, L., Agbandje-McKenna, M., Leichtle, S., Eugene Redmond Jr, D., et al. (2008) · Molecular Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 261

Immune responses to AAV in a phase I study for Canavan disease

McPhee, S. W. J., Janson, C. G., Li, C., Samulski, R. J., Camp, A. S., Francis, J., Shera, D., Lioutermann, L., Feely, M., Freese, A., et al. (2006) · The Journal of Gene Medicine

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 241

Neutralizing antibodies against adeno-associated virus examined prospectively in pediatric patients with hemophilia

Li, C., Narkbunnam, N., Samulski, R. J., Asokan, A., Hu, G., Jacobson, L. J., Manco-Johnson, M. J., Monahan, P. E., & The Joint Outcome Study Investigators (2012) · Gene Therapy

Virus-based gene therapy researchHemophilia Treatment and Research

Cited by 225

Adeno-Associated Virus Vectorology, Manufacturing, and Clinical Applications

Grieger, J. C., & Samulski, R. J. (2012) · Methods in Enzymology

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 199

Titration of AAV-2 particles via a novel capsid ELISA: packaging of genomes can limit production of recombinant AAV-2

Grimm, D., Kern, A., Pawlita, M., Ferrari, F. K., Samulski, R. J., & Kleinschmidt, J. A. (1999) · Gene Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 195

AAV hybrid serotypes: improved vectors for gene delivery

Choi, V., McCarty, D., & Samulski, R. (2005) · Current Gene Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 191

BAX 335 hemophilia b gene therapy clinical trial results: Potential impact of CpG sequences on gene expression

Konkle, B. A., Walsh, C. E., Escobar, M. A., Josephson, N. C., Young, G., von Drygalski, A., McPhee, S. W. J., Samulski, R. J., Bilic, I., de la Rosa, M., et al. (2021) · Blood

Hemophilia Treatment and ResearchVirus-based gene therapy research

Cited by 189

Directed Evolution of a Novel Adeno-associated Virus (AAV) Vector That Crosses the Seizure-compromised Blood–Brain Barrier (BBB)

Gray, S. J., Blake, B. L., Criswell, H. E., Nicolson, S. C., Samulski, R. J., & McCown, T. J. (2010) · Molecular Therapy

Virus-based gene therapy researchBarrier Structure and Function Studies

Cited by 185

Adeno-Associated Virus Type 2 Contains an Integrin α5β1 Binding Domain Essential for Viral Cell Entry

Asokan, A., Hamra, J. B., Govindasamy, L., Agbandje-McKenna, M., & Samulski, R. J. (2006) · Journal of Virology

Virus-based gene therapy researchCell Adhesion Molecules Research

Cited by 183

Separate basic region motifs within the adeno-associated virus capsid proteins are essential for infectivity and assembly

Grieger, J. C., Snowdy, S., & Samulski, R. J. (2006) · Journal of Virology

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 172