Lange, Sven M.

Impact of 100 LRRK2 variants linked to Parkinson's disease on kinase activity and microtubule binding

Kalogeropulou, A. F., Purlyte, E., Tonelli, F., Lange, S. M., Wightman, M., Prescott, A. R., Padmanabhan, S., Sammler, E., & Alessi, D. R. (2022) · Biochemical Journal

Parkinson's Disease Mechanisms and TreatmentsProtein Kinase Regulation and GTPase Signaling

Cited by 129

Human UFSP1 is an active protease that regulates UFM1 maturation and UFMylation

Millrine, D., Cummings, T., Matthews, S. P., Peter, J. J., Magnussen, H. M., Lange, S. M., Macartney, T., Lamoliatte, F., Knebel, A., & Kulathu, Y. (2022) · Cell Reports

Ubiquitin and proteasome pathwaysCancer-related gene regulation

Cited by 71

Mechanism of human PINK1 activation at the TOM complex in a reconstituted system

Raimi, O. G., Ojha, H., Ehses, K., Dederer, V., Lange, S. M., Rivera, C. P., Deegan, T. D., Chen, Y., Wightman, M., Toth, R., et al. (2023) · Science Advances

Parkinson's Disease Mechanisms and TreatmentsMitochondrial Function and Pathology

Cited by 39

A conserved mechanism for the retrieval of polyubiquitinated proteins from cilia

Lange, S. M., Eisert, R. J., & Brown, A. (2025) · Cell

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

Cited by 11

A conserved mechanism for the retrieval of polyubiquitinated proteins from cilia

Lange, S. M., Bennett, J. A., Eisert, R. J., & Brown, A. (2025) · Cell

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

Cited by 11