Abu-Remaileh, Monther

An essential role of the mitochondrial electron transport chain in cell proliferation is to enable aspartate synthesis

Birsoy, K., Wang, T., Chen, W. W., Freinkman, E., Abu-Remaileh, M., & Sabatini, D. M. (2015) · Cell

Cancer, Hypoxia, and MetabolismMitochondrial Function and Pathology

Cited by 1,388

A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate

Pacold, M. E., Brimacombe, K. R., Chan, S. H., Rohde, J. M., Lewis, C. A., Swier, L. J. Y. M., Possemato, R., Chen, W. W., Sullivan, L. B., Fiske, B. P., et al. (2016) · Nature Chemical Biology

Cancer, Hypoxia, and MetabolismBiochemical and Molecular Research

Cited by 553

APOE4/4 is linked to damaging lipid droplets in Alzheimer’s disease microglia

Haney, M. S., Pálovics, R., Munson, C. N., Long, C., Johansson, P. K., Yip, O., Dong, W., Rawat, E., West, E., Schlachetzki, J. C. M., et al. (2024) · Nature

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 536

Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging

Mihaylova, M. M., Cheng, C.-W., Cao, A. Q., Tripathi, S., Mana, M. D., Bauer-Rowe, K. E., Abu-Remaileh, M., Clavain, L., Erdemir, A., Lewis, C. A., et al. (2018) · Cell Stem Cell

Dietary Effects on HealthGenetics, Aging, and Longevity in Model Organisms

Cited by 428

NUFIP1 is a ribosome receptor for starvation-induced ribophagy

Wyant, G. A., Abu-Remaileh, M., Frenkel, E. M., Laqtom, N. N., Dharamdasani, V., Lewis, C. A., Chan, S. H., Heinze, I., Ori, A., & Sabatini, D. M. (2018) · Science

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 363

Maintaining Iron Homeostasis Is the Key Role of Lysosomal Acidity for Cell Proliferation

Weber, R. A., Yen, F. S., Nicholson, S. P. V., Alwaseem, H., Bayraktar, E. C., Alam, M., Timson, R. C., La, K., Abu-Remaileh, M., Molina, H., et al. (2020) · Molecular Cell

Autophagy in Disease and TherapyIron Metabolism and Disorders

Cited by 236

The Batten disease gene product CLN5 is the lysosomal bis(monoacylglycero)phosphate synthase

Medoh, U. N., Hims, A., Chen, J. Y., Ghoochani, A., Nyame, K., Dong, W., & Abu-Remaileh, M. (2023) · Science

Lysosomal Storage Disorders ResearchLipid metabolism and biosynthesis

Cited by 87

Organelle proteomic profiling reveals lysosomal heterogeneity in association with longevity

Yu, Y., Gao, S. M., Guan, Y., Hu, P.-W., Zhang, Q., Liu, J., Jing, B., Zhao, Q., Sabatini, D. M., Abu-Remaileh, M., et al. (2022) · eLife

Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms

Cited by 37

Organelle proteomic profiling reveals lysosomal heterogeneity in association with longevity

Yu, Y., Gao, S. M., Guan, Y., Hu, P.-W., Zhang, Q., Liu, J., Jing, B., Zhao, Q., Sabatini, D. M., Abu-Remaileh, M., et al. (2024) · eLife

Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms

Cited by 37

APOE4/4 is linked to damaging lipid droplets in Alzheimer’s microglia

Haney, M. S., Pálovics, R., Munson, C. N., Long, C., Johansson, P., Yip, O., Dong, W., Rawat, E., West, E., Schlachetzki, J. C., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory)

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 20