Hembrough, Todd

Tumours with class 3 BRAF mutants are sensitive to the inhibition of activated RAS

Yao, Z., Yaeger, R., Rodrik-Outmezguine, V. S., Tao, A., Torres, N. M., Chang, M. T., Drosten, M., Zhao, H., Cecchi, F., Hembrough, T., et al. (2017) · Nature

Melanoma and MAPK PathwaysProtein Kinase Regulation and GTPase Signaling

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Prognostic and predictive impact of circulating tumor DNA in patients with advanced cancers treated with immune checkpoint blockade

Zhang, Q., Luo, J., Wu, S., Si, H., Gao, C., Xu, W., Abdullah, S. E., Higgs, B. W., Dennis, P. A., van der Heijden, M. S., et al. (2020) · Cancer Discovery

Cancer Immunotherapy and BiomarkersCancer Genomics and Diagnostics

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Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition

Wong, G. S., Zhou, J., Liu, J. B., Wu, Z., Xu, X., Li, T., Xu, D., Schumacher, S. E., Puschhof, J., McFarland, J., et al. (2018) · Nature Medicine

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

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An approach to suppress the evolution of resistance in BRAFV600E-mutant cancer

Xue, Y., Martelotto, L., Baslan, T., Vides, A., Solomon, M., Mai, T. T., Chaudhary, N., Riely, G. J., Li, B. T., Scott, K., et al. (2017) · Nature Medicine

Melanoma and MAPK PathwaysCancer Genomics and Diagnostics

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STK11 (LKB1) mutations in metastatic NSCLC: Prognostic value in the real world

Shire, N. J., Klein, A. B., Golozar, A., Collins, J. M., Fraeman, K. H., Nordstrom, B. L., McEwen, R., Hembrough, T., & Rizvi, N. A. (2020) · PLOS ONE

Lung Cancer Treatments and MutationsLung Cancer Research Studies

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Targeted multiplex proteomics for molecular prescreening and biomarker discovery in metastatic colorectal cancer

Serna, G., Ruiz-Pace, F., Cecchi, F., Fasani, R., Jimenez, J., Thyparambil, S., Landolfi, S., Elez, E., Vivancos, A., Hembrough, T., et al. (2019) · Scientific Reports

Colorectal Cancer Treatments and StudiesAdvanced Proteomics Techniques and Applications

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