Nieuwenhuis, Joppe

Gene essentiality and synthetic lethality in haploid human cells

Blomen, V. A., Májek, P., Jae, L. T., Bigenzahn, J. W., Nieuwenhuis, J., Staring, J., Sacco, R., van Diemen, F. R., Olk, N., Stukalov, A., et al. (2015) · Science

Fungal and yeast genetics researchBioinformatics and Genomic Networks

Cited by 857

Vasohibins encode tubulin detyrosinating activity

Nieuwenhuis, J., Adamopoulos, A., Bleijerveld, O. B., Mazouzi, A., Stickel, E., Celie, P., Altelaar, M., Knipscheer, P., Perrakis, A., Blomen, V. A., et al. (2017) · Science

Microtubule and mitosis dynamicsGenetic and Kidney Cyst Diseases

Cited by 266

PLA2G16 represents a switch between entry and clearance of Picornaviridae

Staring, J., von Castelmur, E., Blomen, V. A., van den Hengel, L. G., Brockmann, M., Baggen, J., Thibaut, H. J., Nieuwenhuis, J., Janssen, H., van Kuppeveld, F. J. M., et al. (2017) · Nature

Viral Infections and Immunology Researchinterferon and immune responses

Cited by 201

Genetic wiring maps of single-cell protein states reveal an off-switch for GPCR signalling

Brockmann, M., Blomen, V. A., Nieuwenhuis, J., Stickel, E., Raaben, M., Bleijerveld, O. B., Altelaar, A. F. M., Jae, L. T., & Brummelkamp, T. R. (2017) · Nature

Gene Regulatory Network AnalysisProtein Kinase Regulation and GTPase Signaling

Cited by 140

Posttranslational modification of microtubules by the MATCAP detyrosinase

Landskron, L., Bak, J., Adamopoulos, A., Kaplani, K., Moraiti, M., van den Hengel, L. G., Song, J.-Y., Bleijerveld, O. B., Nieuwenhuis, J., Heidebrecht, T., et al. (2022) · Science

Microtubule and mitosis dynamicsGenetic and Kidney Cyst Diseases

Cited by 78

Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism

Loregger, A., Raaben, M., Nieuwenhuis, J., Tan, J. M. E., Jae, L. T., van den Hengel, L. G., Hendrix, S., van den Berg, M., Scheij, S., Song, J.-Y., et al. (2020) · Nature Communications

Cancer, Lipids, and MetabolismCholesterol and Lipid Metabolism

Cited by 51