Hart, Matthew J.

Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease

Spilman, P., Podlutskaya, N., Hart, M. J., Debnath, J., Gorostiza, O., Bredesen, D., Richardson, A., Strong, R., & Galvan, V. (2010) · PLoS ONE

Alzheimer's disease research and treatmentsAutophagy in Disease and Therapy

Cited by 1,033

The identification and characterization of a GDP-dissociation inhibitor (GDI) for the CDC42Hs protein

Leonard, D., Hart, M. J., Platko, J. V., Eva, A., Henzel, W., Evans, T., & Cerione, R. A. (1992) · Journal of Biological Chemistry

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

Cited by 175

Neuroprotective Sirtuin ratio reversed by ApoE4

Theendakara, V., Patent, A., Peters Libeu, C. A., Philpot, B., Flores, S., Descamps, O., Poksay, K. S., Zhang, Q., Cailing, G., Hart, M., et al. (2013) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 101

An engineered transforming growth factor β (TGF-β) monomer that functions as a dominant negative to block TGF-β signaling

Kim, S. K., Barron, L., Hinck, C. S., Petrunak, E. M., Cano, K. E., Thangirala, A., Iskra, B., Brothers, M., Vonberg, M., Leal, B., et al. (2017) · Journal of Biological Chemistry

TGF-β signaling in diseasesReceptor Mechanisms and Signaling

Cited by 43