Kautz, Léon

Identification of erythroferrone as an erythroid regulator of iron metabolism

Kautz, L., Jung, G., Valore, E. V., Rivella, S., Nemeth, E., & Ganz, T. (2014) · Nature Genetics

Iron Metabolism and DisordersHemoglobinopathies and Related Disorders

Cited by 1,127

Lack of the bone morphogenetic protein BMP6 induces massive iron overload

Meynard, D., Kautz, L., Darnaud, V., Canonne-Hergaux, F., Coppin, H., & Roth, M.-P. (2009) · Nature Genetics

Iron Metabolism and DisordersTGF-β signaling in diseases

Cited by 587

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver

Kautz, L., Meynard, D., Monnier, A., Darnaud, V., Bouvet, R., Wang, R.-H., Deng, C., Vaulont, S., Mosser, J., Coppin, H., et al. (2008) · Blood

Iron Metabolism and DisordersTGF-β signaling in diseases

Cited by 437

Erythroferrone contributes to hepcidin suppression and iron overload in a mouse model of β-thalassemia

Kautz, L., Jung, G., Du, X., Gabayan, V., Chapman, J., Nasoff, M., Nemeth, E., & Ganz, T. (2015) · Blood

Iron Metabolism and DisordersHemoglobinopathies and Related Disorders

Cited by 306

Minihepcidins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis

Ramos, E., Ruchala, P., Goodnough, J. B., Kautz, L., Preza, G. C., Nemeth, E., & Ganz, T. (2012) · Blood

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 213

Induction of activin B by inflammatory stimuli up-regulates expression of the iron-regulatory peptide hepcidin through Smad1/5/8 signaling

Besson-Fournier, C., Latour, C., Kautz, L., Bertrand, J., Ganz, T., Roth, M.-P., & Coppin, H. (2012) · Blood

Iron Metabolism and DisordersTGF-β signaling in diseases

Cited by 179

Erythroferrone contributes to recovery from anemia of inflammation

Kautz, L., Jung, G., Nemeth, E., & Ganz, T. (2014) · Blood

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 152

Immunoassay for human serum erythroferrone

Ganz, T., Jung, G., Naeim, A., Ginzburg, Y., Pakbaz, Z., Walter, P. B., Kautz, L., & Nemeth, E. (2017) · Blood

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 125

Testosterone Perturbs Systemic Iron Balance Through Activation of Epidermal Growth Factor Receptor Signaling in the Liver and Repression of Hepcidin

Latour, C., Kautz, L., Besson-Fournier, C., Island, M.-L., Canonne-Hergaux, F., Loréal, O., Ganz, T., Coppin, H., & Roth, M.-P. (2014) · Hepatology

Iron Metabolism and DisordersTrace Elements in Health

Cited by 120

A variant erythroferrone disrupts iron homeostasis in SF3B1 -mutated myelodysplastic syndrome

Bondu, S., Alary, A.-S., Lefèvre, C., Houy, A., Jung, G., Lefebvre, T., Rombaut, D., Boussaid, I., Bousta, A., Guillonneau, F., et al. (2019) · Science Translational Medicine

Acute Myeloid Leukemia ResearchIron Metabolism and Disorders

Cited by 85