Okuno, Yutaka

Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1.

Rosenbauer, F., Wagner, K., Kutok, J. L., Iwasaki, H., Le Beau, M. M., Okuno, Y., Akashi, K., Fiering, S., & Tenen, D. G. (2004) · Nature Genetics

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 506

PU.1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis.

Huang, G., Zhang, P., Hirai, H., Elf, S., Yan, X., Chen, Z., Koschmieder, S., Okuno, Y., Dayaram, T., Growney, J. D., et al. (2008) · Nature Genetics

Genomics and Chromatin DynamicsAcute Myeloid Leukemia Research

Cited by 259

Potential Autoregulation of Transcription Factor PU.1 by an Upstream Regulatory Element

Okuno, Y., Huang, G., Rosenbauer, F., Evans, E. K., Radomska, H. S., Iwasaki, H., Akashi, K., Moreau-Gachelin, F., Li, Y., Zhang, P., et al. (2005) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsHematopoietic Stem Cell Transplantation

Cited by 174

Regulation of the PU.1 gene by distal elements

Li, Y., Okuno, Y., Zhang, P., Radomska, H. S., Chen, H.-M., Iwasaki, H., Akashi, K., Klemsz, M. J., McKercher, S. R., Maki, R. A., et al. (2001) · Blood

Genomics and Chromatin DynamicsHematopoietic Stem Cell Transplantation

Cited by 110

PU.1 induces apoptosis in myeloma cells through direct transactivation of TRAIL.

Ueno, S., Tatetsu, H., Hata, H., Iino, T., Niiro, H., Akashi, K., Tenen, D. G., Mitsuya, H., & Okuno, Y. (2009) · Oncogene

Multiple Myeloma Research and TreatmentsCell death mechanisms and regulation

Cited by 20