Tsukamoto, Hirotake

Combined Blockade of IL6 and PD-1/PD-L1 Signaling Abrogates Mutual Regulation of Their Immunosuppressive Effects in the Tumor Microenvironment

Tsukamoto, H., Fujieda, K., Miyashita, A., Fukushima, S., Ikeda, T., Kubo, Y., Senju, S., Ihn, H., Nishimura, Y., & Oshiumi, H. (2018) · Cancer Research

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 305

Age-associated increase in lifespan of naive CD4 T cells contributes to T-cell homeostasis but facilitates development of functional defects

Tsukamoto, H., Clise-Dwyer, K., Huston, G. E., Duso, D. K., Buck, A. L., Johnson, L. L., Haynes, L., & Swain, S. L. (2009) · Proceedings of the National Academy of Sciences

T-cell and B-cell ImmunologyGenetics, Aging, and Longevity in Model Organisms

Cited by 166

IL-6-mediated environmental conditioning of defective Th1 differentiation dampens antitumour immune responses in old age

Tsukamoto, H., Senju, S., Matsumura, K., Swain, S. L., & Nishimura, Y. (2015) · Nature Communications

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 104

Soluble IL6R expressed by myeloid cells reduces tumor-specific Th1 differentiation and drives tumor progression

Tsukamoto, H., Fujieda, K., Hirayama, M., Ikeda, T., Yuno, A., Matsumura, K., Fukuma, D., Araki, K., Mizuta, H., Nakayama, H., et al. (2017) · Cancer Research

Cytokine Signaling Pathways and InteractionsT-cell and B-cell Immunology

Cited by 53