Tsigelny, Igor F.

JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation.

Kallunki, T., Su, B., Tsigelny, I., Sluss, H. K., Dérijard, B., Moore, G., Davis, R., & Karin, M. (1994) · Genes & Development

Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases

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Mechanisms of Hybrid Oligomer Formation in the Pathogenesis of Combined Alzheimer's and Parkinson's Diseases

Tsigelny, I. F., Crews, L., Desplats, P., Shaked, G. M., Sharikov, Y., Mizuno, H., Spencer, B., Rockenstein, E., Trejo, M., Platoshyn, O., et al. (2008) · PLoS ONE

Alzheimer's disease research and treatmentsParkinson's Disease Mechanisms and Treatments

Cited by 281

Fibrin drives thromboinflammation and neuropathology in COVID-19

Ryu, J. K., Yan, Z., Montano, M., Sozmen, E. G., Dixit, K., Suryawanshi, R. K., Matsui, Y., Helmy, E., Kaushal, P., Makanani, S. K., et al. (2024) · Nature

COVID-19 Clinical Research StudiesBlood properties and coagulation

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p75 neurotrophin receptor is a clock gene that regulates oscillatory components of circadian and metabolic networks

Baeza-Raja, B., Eckel-Mahan, K., Zhang, L., Vagena, E., Tsigelny, I. F., Sassone-Corsi, P., Ptacek, L. J., & Akassoglou, K. (2013) · Journal of Neuroscience

Circadian rhythm and melatoninSleep and Wakefulness Research

Cited by 44

Synergism in actions of HBV with aflatoxin in cancer development

Jin, J., Kouznetsova, V. L., Kesari, S., & Tsigelny, I. F. (2023) · Toxicology

Mycotoxins in Agriculture and FoodHepatitis B Virus Studies

Cited by 43

Molecular determinants of drug-specific sensitivity for epidermal growth factor receptor (EGFR) exon 19 and 20 mutants in non-small cell lung cancer

Tsigelny, I. F., Wheler, J. J., Greenberg, J. P., Kouznetsova, V. L., Stewart, D. J., Bazhenova, L., & Kurzrock, R. (2015) · Oncotarget

Lung Cancer Treatments and MutationsHER2/EGFR in Cancer Research

Cited by 30

Machine learning model to predict oncologic outcomes for drugs in randomized clinical trials

Schperberg, A. V., Boichard, A., Tsigelny, I. F., Richard, S. B., & Kurzrock, R. (2020) · International Journal of Cancer

Computational Drug Discovery MethodsBreast Cancer Treatment Studies

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