Holland, Christian H.

Benchmark and integration of resources for the estimation of human transcription factor activities

Garcia-Alonso, L., Holland, C. H., Ibrahim, M. M., Turei, D., & Saez-Rodriguez, J. (2019) · Genome Research

Genomics and Chromatin DynamicsGene Regulatory Network Analysis

Cited by 1,122

Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data

Holland, C. H., Tanevski, J., Perales-Patón, J., Gleixner, J., Kumar, M. P., Mereu, E., Joughin, B. A., Stegle, O., Lauffenburger, D. A., Heyn, H., et al. (2020) · Genome Biology

Single-cell and spatial transcriptomicsBioinformatics and Genomic Networks

Cited by 323

Imbalanced gut microbiota fuels hepatocellular carcinoma development by shaping the hepatic inflammatory microenvironment

Schneider, K. M., Mohs, A., Gui, W., Galvez, E. J. C., Candels, L. S., Hoenicke, L., Muthukumarasamy, U., Holland, C. H., Elfers, C., Kilic, K., et al. (2022) · Nature Communications

Gut microbiota and healthImmune cells in cancer

Cited by 225

Hepatocyte-specific NRF2 activation controls fibrogenesis and carcinogenesis in steatohepatitis

Mohs, A., Otto, T., Schneider, K. M., Peltzer, M., Boekschoten, M., Holland, C. H., Hudert, C. A., Kalveram, L., Wiegand, S., Saez-Rodriguez, J., et al. (2021) · Journal of Hepatology

Genomics, phytochemicals, and oxidative stressLiver Disease Diagnosis and Treatment

Cited by 137