Xiong, Yan

Autophagy is required for tolerance of drought and salt stress in plants

Liu, Y., Xiong, Y., & Bassham, D. C. (2009) · Autophagy

Autophagy in Disease and TherapyPlant Stress Responses and Tolerance

Cited by 422

Bridged Proteolysis Targeting Chimera (PROTAC) Enables Degradation of Undruggable Targets

Xiong, Y., Zhong, Y., Yim, H., Yang, X., Park, K.-S., Xie, L., Poulikakos, P. I., Han, X., Xiong, Y., Chen, X., et al. (2022) · Journal of the American Chemical Society

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 154

Inhibiting the coregulator CoREST impairs Foxp3+ Treg function and promotes antitumor immunity

Xiong, Y., Wang, L., Di Giorgio, E., Akimova, T., Beier, U. H., Han, R., Trevisanut, M., Kalin, J. H., Cole, P. A., & Hancock, W. W. (2020) · Journal of Clinical Investigation

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 72

Acetylation targeting chimera enables acetylation of the tumor suppressor p53

Kabir, M., Sun, N., Hu, X., Martin, T. C., Yi, J., Zhong, Y., Xiong, Y., Kaniskan, H. Ü., Gu, W., Parsons, R., et al. (2023) · Journal of the American Chemical Society

Protein Degradation and InhibitorsChemical Synthesis and Analysis

Cited by 65

A Comparative Study of the Pharmacokinetics of Clozapine N-Oxide and Clozapine N-Oxide Hydrochloride Salt in Rhesus Macaques

Allen, D. C., Carlson, T. L., Xiong, Y., Jin, J., Grant, K. A., & Cuzon Carlson, V. C. (2019) · The Journal of Pharmacology and Experimental Therapeutics

Pharmacogenetics and Drug MetabolismSchizophrenia research and treatment

Cited by 17

Design, synthesis, and evaluation of p53Y220C acetylation targeting chimeras (AceTACs)

Hu, X., Kabir, M., Lin, Y., Xiong, Y., Parsons, R. E., Gu, W., & Jin, J. (2024) · Journal of Medicinal Chemistry

Cancer-related Molecular PathwaysProtein Degradation and Inhibitors

Cited by 9