Shaul, Yoav D.

The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1

Sancak, Y., Peterson, T. R., Shaul, Y. D., Lindquist, R. A., Thoreen, C. C., Bar-Peled, L., & Sabatini, D. M. (2008) · Science

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

Cited by 2,773

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

Possemato, R., Marks, K. M., Shaul, Y. D., Pacold, M. E., Kim, D., Birsoy, K., Sethumadhavan, S., Woo, H.-K., Jang, H. G., Jha, A. K., et al. (2011) · Nature

Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism

Cited by 1,683

A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate

Pacold, M. E., Brimacombe, K. R., Chan, S. H., Rohde, J. M., Lewis, C. A., Swier, L. J. Y. M., Possemato, R., Chen, W. W., Sullivan, L. B., Fiske, B. P., et al. (2016) · Nature Chemical Biology

Cancer, Hypoxia, and MetabolismBiochemical and Molecular Research

Cited by 553

The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes

Luu, M., Pautz, S., Kohl, V., Singh, R., Romero, R., Lucas, S., Hofmann, J., Raifer, H., Vachharajani, N., Carrascosa, L. C., et al. (2019) · Nature Communications

Gut microbiota and healthT-cell and B-cell Immunology

Cited by 508

The exostosin glycosyltransferase 1/STAT3 axis is a driver of breast cancer aggressiveness

Solaimuthu, B., Khatib, A., Tanna, M., Karmi, A., Hayashi, A., Abu Rmaileh, A., Lichtenstein, M., Takoe, S., Jolly, M. K., & Shaul, Y. D. (2024) · Proceedings of the National Academy of Sciences

Proteoglycans and glycosaminoglycans researchCancer Cells and Metastasis

Cited by 8