Walz, Gerd

Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways

Simons, M., Gloy, J., Ganner, A., Bullerkotte, A., Bashkurov, M., Krönig, C., Schermer, B., Benzing, T., Cabello, O. A., Jenny, A., et al. (2005) · Nature Genetics

Genetic and Kidney Cyst DiseasesWnt/β-catenin signaling in development and cancer

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Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice

Hartleben, B., Gödel, M., Meyer-Schwesinger, C., Liu, S., Ulrich, T., Köbler, S., Wiech, T., Grahammer, F., Arnold, S. J., Lindenmeyer, M. T., et al. (2010) · Journal of Clinical Investigation

Renal Diseases and GlomerulopathiesAutophagy in Disease and Therapy

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Everolimus in Patients with Autosomal Dominant Polycystic Kidney Disease

Walz, G., Budde, K., Mannaa, M., Nürnberger, J., Wanner, C., Sommerer, C., Kunzendorf, U., Banas, B., Hörl, W. H., Obermüller, N., et al. (2010) · New England Journal of Medicine

Genetic and Kidney Cyst DiseasesTuberous Sclerosis Complex Research

Cited by 587

Role of mTOR in podocyte function and diabetic nephropathy in humans and mice

Gödel, M., Hartleben, B., Herbach, N., Liu, S., Zschiedrich, S., Lu, S., Debreczeni-Mór, A., Lindenmeyer, M. T., Rastaldi, M.-P., Hartleben, G., et al. (2011) · Journal of Clinical Investigation

Renal Diseases and GlomerulopathiesChronic Kidney Disease and Diabetes

Cited by 547

Loss of Nephrocystin-3 Function Can Cause Embryonic Lethality, Meckel-Gruber-like Syndrome, Situs Inversus, and Renal-Hepatic-Pancreatic Dysplasia

Bergmann, C., Fliegauf, M., Brüchle, N. O., Frank, V., Olbrich, H., Kirschner, J., Schermer, B., Schmedding, I., Kispert, A., Kränzlin, B., et al. (2008) · The American Journal of Human Genetics

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

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Autophagy plays a critical role in kidney tubule maintenance, aging and ischemia-reperfusion injury

Liu, S., Hartleben, B., Kretz, O., Wiech, T., Igarashi, P., Mizushima, N., Walz, G., & Huber, T. B. (2012) · Autophagy

Autophagy in Disease and TherapyAcute Kidney Injury Research

Cited by 271

A highly conserved tyrosine of Tim‐3 is phosphorylated upon stimulation by its ligand galectin‐9

van de Weyer, P. S., Muehlfeit, M., Klose, C., Bonventre, J. V., Walz, G., & Kuehn, E. W. (2006) · Biochemical and Biophysical Research Communications

Galectins and Cancer BiologyT-cell and B-cell Immunology

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Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development

Skouloudaki, K., Puetz, M., Simons, M., Courbard, J.-R., Boehlke, C., Hartleben, B., Engel, C., Moeller, M. J., Englert, C., Bollig, F., et al. (2009) · Proceedings of the National Academy of Sciences

Hippo pathway signaling and YAP/TAZDevelopmental Biology and Gene Regulation

Cited by 163

Vps34 Deficiency Reveals the Importance of Endocytosis for Podocyte Homeostasis

Bechtel, W., Helmstädter, M., Balica, J., Hartleben, B., Kiefer, B., Hrnjic, F., Schell, C., Kretz, O., Liu, S., Geist, F., et al. (2013) · Journal of the American Society of Nephrology

Renal Diseases and GlomerulopathiesCellular transport and secretion

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Primary mouse hepatocytes for systems biology approaches: a standardized in vitro system for modelling of signal transduction pathways

Klingmüller, U., Bauer, A., Bohl, S., Nickel, P. J., Breitkopf, K., Dooley, S., Zellmer, S., Kern, C., Merfort, I., Sparna, T., et al. (2006) · IEE Proceedings - Systems Biology

Liver physiology and pathologyGene Regulatory Network Analysis

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mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress

Grahammer, F., Haenisch, N., Steinhardt, F., Sandner, L., Roerden, M., Arnold, F., Cordts, T., Wanner, N., Reichardt, W., Kerjaschki, D., et al. (2014) · Proceedings of the National Academy of Sciences

PI3K/AKT/mTOR signaling in cancerAutophagy in Disease and Therapy

Cited by 109

Loss of Podocyte aPKCλ/ι Causes Polarity Defects and Nephrotic Syndrome

Huber, T. B., Hartleben, B. D., Winkelmann, K., Schneider, L., Becker, J. U., Leitges, M., Walz, G., Haller, H., & Schiffer, M. (2009) · Journal of the American Society of Nephrology

Renal Diseases and GlomerulopathiesRenal and related cancers

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Targeting mTOR Signaling Can Prevent the Progression of FSGS

Zschiedrich, S., Bork, T., Liang, W., Wanner, N., Eulenbruch, K., Munder, S., Hartleben, B., Kretz, O., Gerber, S., Simons, M., et al. (2017) · Journal of the American Society of Nephrology

Renal Diseases and GlomerulopathiesPI3K/AKT/mTOR signaling in cancer

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Inversin relays Frizzled-8 signals to promote proximal pronephros development

Lienkamp, S., Ganner, A., Boehlke, C., Schmidt, T., Arnold, S. J., Schäfer, T., Romaker, D., Schuler, J., Hoff, S., Powelske, C., et al. (2010) · Proceedings of the National Academy of Sciences

Renal and related cancersGenetic and Kidney Cyst Diseases

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Role of the polarity protein Scribble for podocyte differentiation and maintenance

Hartleben, B., Widmeier, E., Wanner, N., Schmidts, M., Kim, S. T., Schneider, L., Mayer, B., Kerjaschki, D., Miner, J. H., Walz, G., et al. (2012) · PLoS ONE

Renal Diseases and GlomerulopathiesRenal and related cancers

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PRKCSH/80K-H, the protein mutated in polycystic liver disease, protects polycystin-2/TRPP2 against HERP-mediated degradation

Gao, H., Wang, Y., Wegierski, T., Skouloudaki, K., Pütz, M., Fu, X., Engel, C., Boehlke, C., Peng, H., Kuehn, E. W., et al. (2010) · Human Molecular Genetics

Genetic and Kidney Cyst DiseasesEndoplasmic Reticulum Stress and Disease

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Results from the German Chronic Kidney Disease (GCKD) study support association of relative telomere length with mortality in a large cohort of patients with moderate chronic kidney disease

Fazzini, F., Lamina, C., Raschenberger, J., Schultheiss, U. T., Kotsis, F., Schönherr, S., Weissensteiner, H., Forer, L., Steinbrenner, I., Meiselbach, H., et al. (2020) · Kidney International

Telomeres, Telomerase, and SenescenceChronic Kidney Disease and Diabetes

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