Ioerger, Thomas R.

PHENIX : building new software for automated crystallographic structure determination

Adams, P. D., Grosse-Kunstleve, R. W., Hung, L.-W., Ioerger, T. R., McCoy, A. J., Moriarty, N. W., Read, R. J., Sacchettini, J. C., Sauter, N. K., & Terwilliger, T. C. (2002) · Acta Crystallographica Section D Biological Crystallography

Enzyme Structure and FunctionCrystal structures of chemical compounds

Cited by 4,361

High-Resolution Phenotypic Profiling Defines Genes Essential for Mycobacterial Growth and Cholesterol Catabolism

Griffin, J. E., Gawronski, J. D., DeJesus, M. A., Ioerger, T. R., Akerley, B. J., & Sassetti, C. M. (2011) · PLoS Pathogens

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 1,048

Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing

Lin, P. L., Ford, C. B., Coleman, M. T., Myers, A. J., Gawande, R., Ioerger, T., Sacchettini, J., Fortune, S. M., & Flynn, J. L. (2014) · Nature Medicine

Tuberculosis Research and EpidemiologyImmune responses and vaccinations

Cited by 533

Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection

Ford, C. B., Lin, P. L., Chase, M. R., Shah, R. R., Iartchouk, O., Galagan, J., Mohaideen, N., Ioerger, T. R., Sacchettini, J. C., Lipsitch, M., et al. (2011) · Nature Genetics

Tuberculosis Research and EpidemiologyInfectious Diseases and Tuberculosis

Cited by 437

Tryptophan Biosynthesis Protects Mycobacteria from CD4 T-Cell-Mediated Killing

Zhang, Y. J., Reddy, M. C., Ioerger, T. R., Rothchild, A. C., Dartois, V., Schuster, B. M., Trauner, A., Wallis, D., Galaviz, S., Huttenhower, C., et al. (2013) · Cell

Tuberculosis Research and EpidemiologyImmune responses and vaccinations

Cited by 351

Leaderless Transcripts and Small Proteins Are Common Features of the Mycobacterial Translational Landscape

Shell, S. S., Wang, J., Lapierre, P., Mir, M., Chase, M. R., Pyle, M. M., Gawande, R., Ahmad, R., Sarracino, D. A., Ioerger, T. R., et al. (2015) · PLOS Genetics

RNA and protein synthesis mechanismsBacterial Genetics and Biotechnology

Cited by 238

Maturing Mycobacterium smegmatis peptidoglycan requires non-canonical crosslinks to maintain shape

Baranowski, C., Welsh, M. A., Sham, L.-T., Eskandarian, H. A., Lim, H. C., Kieser, K. J., Wagner, J. C., McKinney, J. D., Fantner, G. E., Ioerger, T. R., et al. (2018) · eLife

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 132

Chemical Genetic Interaction Profiling Reveals Determinants of Intrinsic Antibiotic Resistance in Mycobacterium tuberculosis

Xu, W., DeJesus, M. A., Rücker, N., Engelhart, C. A., Wright, M. G., Healy, C., Lin, K., Wang, R., Park, S. W., Ioerger, T. R., et al. (2017) · Antimicrobial Agents and Chemotherapy

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 115

Genome-wide Phenotypic Profiling Identifies and Categorizes Genes Required for Mycobacterial Low Iron Fitness

Dragset, M. S., Ioerger, T. R., Zhang, Y. J., Mærk, M., Ginbot, Z., Sacchettini, J. C., Flo, T. H., Rubin, E. J., & Steigedal, M. (2019) · Scientific Reports

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 49

Transposon mutagenesis in Mycobacterium abscessus identifies an essential penicillin-binding protein involved in septal peptidoglycan synthesis and antibiotic sensitivity

Akusobi, C., Benghomari, B. S., Zhu, J., Wolf, I. D., Singhvi, S., Dulberger, C. L., Ioerger, T. R., & Rubin, E. J. (2022) · eLife

Mycobacterium research and diagnosisBacterial Genetics and Biotechnology

Cited by 45