Mussolino, Claudio

A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity

Mussolino, C., Morbitzer, R., Lütge, F., Dannemann, N., Lahaye, T., & Cathomen, T. (2011) · Nucleic Acids Research

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 714

Differential integrity of TALE nuclease genes following adenoviral and lentiviral vector gene transfer into human cells

Holkers, M., Maggio, I., Liu, J., Janssen, J. M., Miselli, F., Mussolino, C., Recchia, A., Cathomen, T., & Gonçalves, M. A. F. V. (2013) · Nucleic Acids Research

Virus-based gene therapy researchCRISPR and Genetic Engineering

Cited by 312

Streptococcus thermophilus CRISPR-cas9 systems enable specific editing of the human genome

Müller, M., Lee, C. M., Gasiunas, G., Davis, T. H., Cradick, T. J., Siksnys, V., Bao, G., Cathomen, T., & Mussolino, C. (2016) · Molecular Therapy

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 254

Novel adeno-associated virus serotypes efficiently transduce murine photoreceptors

Allocca, M., Mussolino, C., Garcia-Hoyos, M., Sanges, D., Iodice, C., Petrillo, M., Vandenberghe, L. H., Wilson, J. M., Marigo, V., Surace, E. M., et al. (2007) · Journal of Virology

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 246

Inactivation of hepatitis B virus replication in cultured cells and in vivo with engineered transcription activator-like effector nucleases

Bloom, K., Ely, A., Mussolino, C., Cathomen, T., & Arbuthnot, P. (2013) · Molecular Therapy

Hepatitis B Virus StudiesCRISPR and Genetic Engineering

Cited by 217

AAV-mediated photoreceptor transduction of the pig cone-enriched retina

Mussolino, C., della Corte, M., Rossi, S., Viola, F., Di Vicino, U., Marrocco, E., Neglia, S., Doria, M., Testa, F., Giovannoni, R., et al. (2011) · Gene Therapy

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 102

Automated generation of gene-edited CAR T cells at clinical scale

Alzubi, J., Lock, D., Rhiel, M., Schmitz, S., Wild, S., Mussolino, C., Hildenbeutel, M., Brandes, C., Rositzka, J., Lennartz, S., et al. (2021) · Molecular Therapy - Methods & Clinical Development

CAR-T cell therapy researchCRISPR and Genetic Engineering

Cited by 53