Leimkühler, Silke

Structure and function of mammalian aldehyde oxidases

Terao, M., Romão, M. J., Leimkühler, S., Bolis, M., Fratelli, M., Coelho, C., Santos-Silva, T., & Garattini, E. (2016) · Archives of Toxicology

Pharmacogenetics and Drug MetabolismEnzyme Structure and Function

Cited by 112

Eprenetapopt triggers ferroptosis, inhibits NFS1 cysteine desulfurase, and synergizes with serine and glycine dietary restriction

Fujihara, K. M., Zhang, B. Z., Jackson, T. D., Ogunkola, M. O., Nijagal, B., Milne, J. V., Sallman, D. A., Ang, C.-S., Nikolic, I., Kearney, C. J., et al. (2022) · Science Advances

Ferroptosis and cancer prognosisSulfur Compounds in Biology

Cited by 102

The molybdenum active site of Formate dehydrogenase is capable of catalyzing C–H bond cleavage and oxygen atom transfer reactions

Hartmann, T., Schrapers, P., Utesch, T., Nimtz, M., Rippers, Y., Dau, H., Mroginski, M. A., Haumann, M., & Leimkühler, S. (2016) · Biochemistry

Metalloenzymes and iron-sulfur proteinsMetal-Catalyzed Oxygenation Mechanisms

Cited by 70

A single nucleotide polymorphism causes enhanced radical oxygen species production by human aldehyde oxidase

Foti, A., Dorendorf, F., & Leimkühler, S. (2017) · PLOS ONE

Pharmacogenetics and Drug MetabolismMetal-Catalyzed Oxygenation Mechanisms

Cited by 26

Protein Dynamics Affect O 2 -Stability of Group B [FeFe]-Hydrogenase from Thermosediminibacter oceani

Ghosh, S., Das, C. K., Uddin, S., Stripp, S. T., Engelbrecht, V., Winkler, M., Leimkühler, S., Brocks, C., Duan, J., Schäfer, L. V., et al. (2025) · Journal of the American Chemical Society

Metalloenzymes and iron-sulfur proteinsMetal-Catalyzed Oxygenation Mechanisms

Cited by 21

Protein dynamics affect O 2 -stability of Group B [FeFe]-hydrogenase from Thermosediminibacter oceani

Ghosh, S., Das, C. K., Uddin, S., Stripp, S. T., Engelbrecht, V., Winkler, M., Leimkühler, S., Brocks, C., Duan, J., Schäfer, L. V., et al. (2025) · Journal of the American Chemical Society

Metalloenzymes and iron-sulfur proteinsMetal-Catalyzed Oxygenation Mechanisms

Cited by 21