Sharma, Shruti

IFI16 is an innate immune sensor for intracellular DNA

Unterholzner, L., Keating, S. E., Baran, M., Horan, K. A., Jensen, S. B., Sharma, S., Sirois, C. M., Jin, T., Latz, E., Xiao, T. S., et al. (2010) · Nature Immunology

interferon and immune responsesImmune Response and Inflammation

Cited by 1,643

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

Rathinam, V. A. K., Jiang, Z., Waggoner, S. N., Sharma, S., Cole, L. E., Waggoner, L., Vanaja, S. K., Monks, B. G., Ganesan, S., Latz, E., et al. (2010) · Nature Immunology

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 1,331

Multiple cathepsins promote pro-IL-1β synthesis and NLRP3-mediated IL-1β activation

Orlowski, G. M., Colbert, J. D., Sharma, S., Bogyo, M., Robertson, S. A., & Rock, K. L. (2015) · The Journal of Immunology

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 268

Clonal evolution underlying leukemia progression and Richter transformation in patients with ibrutinib-relapsed CLL

Kadri, S., Lee, J., Fitzpatrick, C., Galanina, N., Sukhanova, M., Venkataraman, G., Sharma, S., Long, B., Petras, K., Theissen, M., et al. (2017) · Blood Advances

Chronic Lymphocytic Leukemia ResearchAcute Myeloid Leukemia Research

Cited by 133

Leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation: clinical and genetic characterization and target for therapy

van Berge, L., Hamilton, E. M., Linnankivi, T., Uziel, G., Steenweg, M. E., Isohanni, P., Wolf, N. I., Krageloh-Mann, I., Brautaset, N. J., Andrews, P. I., et al. (2014) · Brain

Metabolism and Genetic DisordersMitochondrial Function and Pathology

Cited by 109

Identification of a structurally novel BTK mutation that drives ibrutinib resistance in CLL

Sharma, S., Galanina, N., Guo, A., Lee, J., Kadri, S., Van Slambrouck, C., Long, B., Wang, W., Ming, M., Furtado, L. V., et al. (2016) · Oncotarget

Chronic Lymphocytic Leukemia ResearchLymphoma Diagnosis and Treatment

Cited by 90

Lipopolysaccharide-induced lung injury involves the nitration-mediated activation of RhoA

Rafikov, R., Dimitropoulou, C., Aggarwal, S., Kangath, A., Gross, C., Pardo, D., Sharma, S., Jezierska-Drutel, A., Patel, V., Snead, C., et al. (2014) · Journal of Biological Chemistry

Protein Kinase Regulation and GTPase SignalingNitric Oxide and Endothelin Effects

Cited by 67