Simon, Matthew J.

Aquaporin-4-dependent glymphatic solute transport in the rodent brain

Mestre, H., Hablitz, L. M., Xavier, A. L., Feng, W., Zou, W., Pu, T., Monai, H., Murlidharan, G., Castellanos Rivera, R. M., Simon, M. J., et al. (2018) · eLife

Cerebrospinal fluid and hydrocephalusIon Transport and Channel Regulation

Cited by 738

Association of Perivascular Localization of Aquaporin-4 With Cognition and Alzheimer Disease in Aging Brains

Zeppenfeld, D. M., Simon, M., Haswell, J. D., D’Abreo, D., Murchison, C., Quinn, J. F., Grafe, M. R., Woltjer, R. L., Kaye, J., & Iliff, J. J. (2017) · JAMA Neurology

Cerebrospinal fluid and hydrocephalusAlzheimer's disease research and treatments

Cited by 651

Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic

Logan, T., Simon, M. J., Rana, A., Cherf, G. M., Srivastava, A., Davis, S. S., Low, R. L. Y., Chiu, C.-L., Fang, M., Huang, F., et al. (2021) · Cell

Lysosomal Storage Disorders ResearchAmyotrophic Lateral Sclerosis Research

Cited by 233

Targeting the transferrin receptor to transport antisense oligonucleotides across the mammalian blood-brain barrier

Barker, S. J., Thayer, M. B., Kim, C., Tatarakis, D., Simon, M. J., Dial, R., Nilewski, L., Wells, R. C., Zhou, Y., Afetian, M., et al. (2024) · Science Translational Medicine

RNA Interference and Gene DeliveryBarrier Structure and Function Studies

Cited by 142

The effects of noncoding aquaporin‐4 single‐nucleotide polymorphisms on cognition and functional progression of Alzheimer's disease

Burfeind, K. G., Murchison, C. F., Westaway, S. K., Simon, M. J., Erten‐Lyons, D., Kaye, J. A., Quinn, J. F., & Iliff, J. J. (2017) · Alzheimer's & Dementia: Translational Research & Clinical Interventions

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 136

Lysosomal functions of progranulin and implications for treatment of frontotemporal dementia

Simon, M. J., Logan, T., DeVos, S. L., & Di Paolo, G. (2023) · Trends in Cell Biology

Lysosomal Storage Disorders ResearchAmyotrophic Lateral Sclerosis Research

Cited by 94

Transcriptional network analysis of human astrocytic endfoot genes reveals region-specific associations with dementia status and tau pathology

Simon, M. J., Wang, M. X., Murchison, C. F., Roese, N. E., Boespflug, E. L., Woltjer, R. L., & Iliff, J. J. (2018) · Scientific Reports

Alzheimer's disease research and treatmentsCerebrospinal fluid and hydrocephalus

Cited by 71

Lysosomes cell autonomously regulate myeloid cell states and immune responses

Tejwani, L., Balak, C., Skuja, L. L., Tatarakis, D., Rana, A., Fitzgerald, G. A., Ha, C., Lunkes de Melo, G., Sun, E. W., Heffner, C. M., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory)

Neuroinflammation and Neurodegeneration MechanismsAutophagy in Disease and Therapy

Cited by 4