Bargonetti, Jill

A Single Nucleotide Polymorphism in the MDM2 Promoter Attenuates the p53 Tumor Suppressor Pathway and Accelerates Tumor Formation in Humans

Bond, G. L., Hu, W., Bond, E. E., Robins, H., Lutzker, S. G., Arva, N. C., Bargonetti, J., Bartel, F., Taubert, H., Wuerl, P., et al. (2004) · Cell

Cancer-related Molecular PathwaysPI3K/AKT/mTOR signaling in cancer

Cited by 1,265

Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway

Freed-Pastor, W. A., Mizuno, H., Zhao, X., Langerød, A., Moon, S.-H., Rodriguez-Barrueco, R., Barsotti, A., Chicas, A., Li, W., Polotskaia, A., et al. (2012) · Cell

Cancer, Lipids, and MetabolismCancer-related Molecular Pathways

Cited by 865

Wild-type p53 activates transcription in vitro

Farmer, G., Bargonetti, J., Zhu, H., Friedman, P., Prywes, R., & Prives, C. (1992) · Nature

Cancer-related Molecular PathwaysGenomics and Chromatin Dynamics

Cited by 579

Multiple roles of the tumor suppressor p53

Bargonetti, J., & Manfredi, J. J. (2002) · Current Opinion in Oncology

Cancer-related Molecular PathwaysCell death mechanisms and regulation

Cited by 332

Mutant p53 in MDA-MB-231 breast cancer cells is stabilized by elevated phospholipase D activity and contributes to survival signals generated by phospholipase D

Hui, L., Zheng, Y., Yan, Y., Bargonetti, J., & Foster, D. A. (2006) · Oncogene

Cancer-related Molecular PathwaysPI3K/AKT/mTOR signaling in cancer

Cited by 218

A p53-independent role of Mdm2 in estrogen-mediated activation of breast cancer cell proliferation

Brekman, A., Singh, K. E., Polotskaia, A., Kundu, N., & Bargonetti, J. (2011) · Breast Cancer Research

Cancer-related Molecular PathwaysEstrogen and related hormone effects

Cited by 87