Castoreno, Adam

Selection of GalNAc-conjugated siRNAs with limited off-target-driven rat hepatotoxicity

Janas, M. M., Schlegel, M. K., Harbison, C. E., Yilmaz, V. O., Jiang, Y., Parmar, R., Zlatev, I., Castoreno, A., Xu, H., Shulga-Morskaya, S., et al. (2018) · Nature Communications

RNA Interference and Gene DeliveryDrug-Induced Hepatotoxicity and Protection

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Expanding RNAi therapeutics to extrahepatic tissues with lipophilic conjugates

Brown, K. M., Nair, J. K., Janas, M. M., Anglero-Rodriguez, Y. I., Dang, L. T. H., Peng, H., Theile, C. S., Castellanos-Rizaldos, E., Brown, C., Foster, D., et al. (2022) · Nature Biotechnology

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

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An investigational RNAi therapeutic targeting factor XII (ALN-F12) for the treatment of hereditary Angioedema

Akinc, A., Liu, J., Qin, J., Castoreno, A., Schlegel, M., Maier, M., Fitzgerald, K., & Meyers, R. (2016) · Journal of Allergy and Clinical Immunology

Coagulation, Bradykinin, Polyphosphates, and AngioedemaHemophilia Treatment and Research

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