Yang, Xiaobao

Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target

Zhang, B., Li, J., Yang, X., Wu, L., Zhang, J., Yang, Y., Zhao, Y., Zhang, L., Yang, X., Yang, X., et al. (2019) · Cell

Tuberculosis Research and EpidemiologyDrug Transport and Resistance Mechanisms

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Proteolysis Targeting Chimeras (PROTACs) of Anaplastic Lymphoma Kinase (ALK)

Zhang, C., Han, X.-R., Yang, X., Jiang, B., Liu, J., Xiong, Y., & Jin, J. (2018) · European Journal of Medicinal Chemistry

Protein Degradation and InhibitorsLung Cancer Treatments and Mutations

Cited by 226

DeepPROTACs is a deep learning-based targeted degradation predictor for PROTACs

Li, F., Hu, Q., Zhang, X., Sun, R., Liu, Z., Wu, S., Tian, S., Ma, X., Dai, Z., Yang, X., et al. (2022) · Nature Communications

Protein Degradation and InhibitorsComputational Drug Discovery Methods

Cited by 159

Bridged Proteolysis Targeting Chimera (PROTAC) Enables Degradation of Undruggable Targets

Xiong, Y., Zhong, Y., Yim, H., Yang, X., Park, K.-S., Xie, L., Poulikakos, P. I., Han, X., Xiong, Y., Chen, X., et al. (2022) · Journal of the American Chemical Society

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 154

Discovery of SIAIS178 as an Effective BCR-ABL Degrader by Recruiting Von Hippel–Lindau (VHL) E3 Ubiquitin Ligase

Zhao, Q., Ren, C., Liu, L., Chen, J., Shao, Y., Sun, N., Sun, R., Kong, Y., Ding, X., Zhang, X., et al. (2019) · Journal of Medicinal Chemistry

Protein Degradation and InhibitorsChronic Myeloid Leukemia Treatments

Cited by 134