Wilson, James M.

AAV9 targets cone photoreceptors in the nonhuman primate retina

Vandenberghe, L. H., Bell, P., Maguire, A. M., Xiao, R., Hopkins, T. B., Grant, R., Bennett, J., & Wilson, J. M. (2013) · PLoS ONE

Retinal Development and DisordersVirus-based gene therapy research

Cited by 97

Efficient trans-splicing in the retina expands the utility of adeno-associated virus as a vector for gene therapy

Reich, S. J., Auricchio, A., Hildinger, M., Glover, E., Maguire, A. M., Wilson, J. M., & Bennett, J. (2003) · Human Gene Therapy

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 96

Neonatal systemic AAV induces tolerance to CNS gene therapy in MPS I dogs and nonhuman primates

Hinderer, C., Bell, P., Louboutin, J.-P., Zhu, Y., Yu, H., Lin, G., Choa, R., Gurda, B. L., Bagel, J., O'Donnell, P., et al. (2015) · Molecular Therapy

Virus-based gene therapy researchLysosomal Storage Disorders Research

Cited by 85

Utility of PEGylated recombinant adeno-associated viruses for gene transfer

Le, H. T., Yu, Q.-C., Wilson, J. M., & Croyle, M. A. (2005) · Journal of Controlled Release

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 82

High-dose systemic adeno-associated virus vector administration causes liver and sinusoidal endothelial cell injury

Hordeaux, J., Lamontagne, R. J., Song, C., Buchlis, G., Dyer, C., Buza, E. L., Ramezani, A., Wielechowski, E., Greig, J. A., Chichester, J. A., et al. (2024) · Molecular Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 81

Toxicology Study of Intra-Cisterna Magna Adeno-Associated Virus 9 Expressing Iduronate-2-Sulfatase in Rhesus Macaques

Hordeaux, J., Hinderer, C., Goode, T., Buza, E. L., Bell, P., Calcedo, R., Richman, L. K., & Wilson, J. M. (2018) · Molecular Therapy - Methods & Clinical Development

Virus-based gene therapy researchLysosomal Storage Disorders Research

Cited by 81

Class I-restricted T-cell responses to a polymorphic peptide in a gene therapy clinical trial for α-1-antitrypsin deficiency

Calcedo, R., Somanathan, S., Qin, Q., Betts, M. R., Rech, A. J., Vonderheide, R. H., Mueller, C., Flotte, T. R., & Wilson, J. M. (2017) · Proceedings of the National Academy of Sciences

Virus-based gene therapy researchImmunotherapy and Immune Responses

Cited by 79

AAV natural infection induces broad cross-neutralizing antibody responses to multiple AAV serotypes in chimpanzees

Calcedo, R., & Wilson, J. M. (2016) · Human Gene Therapy Clinical Development

Virus-based gene therapy researchSARS-CoV-2 and COVID-19 Research

Cited by 77

TLR9 signaling mediates adaptive immunity following systemic AAV gene therapy

Ashley, S. N., Somanathan, S., Giles, A. R., & Wilson, J. M. (2019) · Cellular Immunology

Virus-based gene therapy researchImmunotherapy and Immune Responses

Cited by 67

Vaccines Based on Novel Adeno-Associated Virus Vectors Elicit Aberrant CD8+T-Cell Responses in Mice

Lin, J., Zhi, Y., Mays, L., & Wilson, J. M. (2007) · Journal of Virology

Virus-based gene therapy researchHIV Research and Treatment

Cited by 66

Non-Clinical Study Examining AAV8.TBG.hLDLR Vector-Associated Toxicity in Chow-Fed Wild-Type and LDLR +/− Rhesus Macaques

Greig, J. A., Limberis, M. P., Bell, P., Chen, S.-J., Calcedo, R., Rader, D. J., & Wilson, J. M. (2017) · Human Gene Therapy Clinical Development

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 56

Complete Prevention of Atherosclerosis in ApoE-Deficient Mice by Hepatic Human ApoE Gene Transfer With Adeno-Associated Virus Serotypes 7 and 8

Kitajima, K., Marchadier, D. H. L., Miller, G. C., Gao, G.-P., Wilson, J. M., & Rader, D. J. (2006) · Arteriosclerosis, Thrombosis, and Vascular Biology

Virus-based gene therapy researchCholesterol and Lipid Metabolism

Cited by 54

Impact of Preexisting Vector Immunity on the Efficacy of Adeno-Associated Virus-Based HIV-1 Gag Vaccines

Lin, J., Calcedo, R., Vandenberghe, L. H., Figueredo, J. M., & Wilson, J. M. (2008) · Human Gene Therapy

Virus-based gene therapy researchHIV Research and Treatment

Cited by 53

AAV8-antiVEGFfab Ocular Gene Transfer for Neovascular Age-Related Macular Degeneration

Liu, Y., Fortmann, S. D., Shen, J., Wielechowski, E., Tretiakova, A., Yoo, S., Kozarsky, K., Wang, J., Wilson, J. M., & Campochiaro, P. A. (2018) · Molecular Therapy

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 51

Delivery of Adeno-Associated Virus Vectors to the Fetal Retina: Impact of Viral Capsid Proteins on Retinal Neuronal Progenitor Transduction

Surace, E. M., Auricchio, A., Reich, S. J., Rex, T., Glover, E., Pineles, S., Tang, W., O'Connor, E., Lyubarsky, A., Savchenko, A., et al. (2003) · Journal of Virology

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 46

Effects of self-complementarity, codon optimization, transgene, and dose on liver transduction with AAV8

Bell, P., Wang, L., Chen, S.-J., Yu, H., Zhu, Y., Nayal, M., He, Z., White, J., Lebel-Hagan, D., & Wilson, J. M. (2016) · Human Gene Therapy Methods

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 26

Immune transgene-dependent myocarditis in macaques after systemic administration of adeno-associated virus expressing human acid alpha-glucosidase

Hordeaux, J., Ramezani, A., Tuske, S., Mehta, N., Song, C., Lynch, A., Lupino, K., Chichester, J. A., Buza, E. L., Dyer, C., et al. (2023) · Frontiers in Immunology

Virus-based gene therapy researchLysosomal Storage Disorders Research

Cited by 23

Correction: AAV9 Targets Cone Photoreceptors in the Nonhuman Primate Retina

Vandenberghe, L. H., Bell, P., Maguire, A. M., Xiao, R., Hopkins, T. B., Grant, R., Bennett, J., & Wilson, J. M. (2013) · PLoS ONE

Retinal Development and DisordersVirus-based gene therapy research

Cited by 16

Identification of the murine AAVrh32.33 capsid-specific CD8+ T cell epitopes

Mays, L. E., & Wilson, J. M. (2009) · The Journal of Gene Medicine

Virus-based gene therapy researchImmunotherapy and Immune Responses

Cited by 13