Hantraye, Philippe

The JAK/STAT3 pathway is a common inducer of astrocyte reactivity in Alzheimer’s and Huntington’s diseases

Ben Haim, L., Ceyzériat, K., Carrillo-de Sauvage, M. A., Aubry, F., Auregan, G., Guillermier, M., Ruiz, M., Petit, F., Houitte, D., Faivre, E., et al. (2015) · The Journal of Neuroscience

Neuroinflammation and Neurodegeneration MechanismsCytokine Signaling Pathways and Interactions

Cited by 335

Modulation of astrocyte reactivity improves functional deficits in mouse models of Alzheimer’s disease

Ceyzériat, K., Ben Haim, L., Denizot, A., Pommier, D., Matos, M., Guillemaud, O., Palomares, M.-A., Abjean, L., Petit, F., Gipchtein, P., et al. (2018) · Acta Neuropathologica Communications

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 256

BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities

Quesseveur, G., David, D. J., Gaillard, M. C., Pla, P., Wu, M. V., Nguyen, H. T., Nicolas, V, Auregan, G., David, I., Dranovsky, A., et al. (2013) · Translational Psychiatry

Neurogenesis and neuroplasticity mechanismsTreatment of Major Depression

Cited by 235

Dopamine Gene Therapy for Parkinson’s Disease in a Nonhuman Primate Without Associated Dyskinesia

Jarraya, B., Boulet, S., Scott Ralph, G., Jan, C., Bonvento, G., Azzouz, M., Miskin, J. E., Shin, M., Delzescaux, T., Drouot, X., et al. (2009) · Science Translational Medicine

Parkinson's Disease Mechanisms and TreatmentsVirus-based gene therapy research

Cited by 186

Engineered lentiviral vector targeting astrocytes In vivo

Colin, A., Faideau, M., Dufour, N., Auregan, G., Hassig, R., Andrieu, T., Brouillet, E., Hantraye, P., Bonvento, G., & Déglon, N. (2009) · Glia

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 158

Increased microglial activation in patients with Parkinson disease using [18F]-DPA714 TSPO PET imaging

Lavisse, S., Goutal, S., Wimberley, C., Tonietto, M., Bottlaender, M., Gervais, P., Kuhnast, B., Peyronneau, M.-A., Barret, O., Lagarde, J., et al. (2021) · Parkinsonism & Related Disorders

Neuroinflammation and Neurodegeneration MechanismsParkinson's Disease Mechanisms and Treatments

Cited by 127

Diffusion-weighted magnetic resonance spectroscopy enables cell-specific monitoring of astrocyte reactivity in vivo

Ligneul, C., Palombo, M., Hernández-Garzón, E., Carrillo-de Sauvage, M.-A., Flament, J., Hantraye, P., Brouillet, E., Bonvento, G., Escartin, C., & Valette, J. (2019) · NeuroImage

Advanced MRI Techniques and ApplicationsAdvanced Neuroimaging Techniques and Applications

Cited by 77

The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin

Galvan, L., Francelle, L., Gaillard, M.-C., de Longprez, L., Carrillo-de Sauvage, M.-A., Liot, G., Cambon, K., Stimmer, L., Luccantoni, S., Flament, J., et al. (2018) · Brain

Genetic Neurodegenerative DiseasesGenetics and Neurodevelopmental Disorders

Cited by 47

In vivo bidirectional modulatory effect of benzodiazepine receptor ligands on GABAergic transmission evaluated by positron emission tomography in non-human primates

Brouillet, E., Chavoix, C., Bottlaender, M., Khalili-Varasteh, M., Hantraye, P., Fournier, D., Dodd, R. H., & Mazière, M. (1991) · Brain Research

Neuroscience and Neuropharmacology ResearchReceptor Mechanisms and Signaling

Cited by 37

THY-Tau22 mouse model accumulates more tauopathy at late stage of the disease in response to microglia deactivation through TREM2 deficiency

Vautheny, A., Duwat, C., Aurégan, G., Joséphine, C., Hérard, A.-S., Jan, C., Mitja, J., Gipchtein, P., Gaillard, M.-C., Buée, L., et al. (2021) · Neurobiology of Disease

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 28