Goertsen, David

AAV capsid variants with brain-wide transgene expression and decreased liver targeting after intravenous delivery in mouse and marmoset

Goertsen, D., Flytzanis, N. C., Goeden, N., Chuapoco, M. R., Cummins, A., Chen, Y., Fan, Y., Zhang, Q., Sharma, J., Duan, Y., et al. (2022) · Nature Neuroscience

Virus-based gene therapy researchRNA Interference and Gene Delivery

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Adeno-Associated Virus Toolkit to Target Diverse Brain Cells

Challis, R. C., Ravindra Kumar, S., Chen, X., Goertsen, D., Coughlin, G. M., Hori, A. M., Chuapoco, M. R., Otis, T. S., Miles, T. F., & Gradinaru, V. (2022) · Annual Review of Neuroscience

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 148

Primate-conserved Carbonic Anhydrase IV and murine-restricted Ly6c1 are new targets for crossing the blood-brain barrier

Shay, T. F., Sullivan, E. E., Ding, X., Chen, X., Kumar, S. R., Goertsen, D., Brown, D., Vielmetter, J., Borsos, M., Lam, A. W., et al. (2023) · Science Advances

Barrier Structure and Function StudiesVirus-based gene therapy research

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