Wiek, Constanze

Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene

Meindl, A., Hellebrand, H., Wiek, C., Erven, V., Wappenschmidt, B., Niederacher, D., Freund, M., Lichtner, P., Hartmann, L., Schaal, H., et al. (2010) · Nature Genetics

BRCA gene mutations in cancerDNA Repair Mechanisms

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Mutation of the RAD51C gene in a Fanconi anemia–like disorder

Vaz, F., Hanenberg, H., Schuster, B., Barker, K., Wiek, C., Erven, V., Neveling, K., Endt, D., Kesterton, I., Autore, F., et al. (2010) · Nature Genetics

DNA Repair MechanismsBlood disorders and treatments

Cited by 408

Targeting Ewing sarcoma with activated and GD2-specific chimeric antigen receptor-engineered human NK cells induces upregulation of immune-inhibitory HLA-G

Kailayangiri, S., Altvater, B., Spurny, C., Jamitzky, S., Schelhaas, S., Jacobs, A. H., Wiek, C., Roellecke, K., Hanenberg, H., Hartmann, W., et al. (2017) · OncoImmunology

Immune Cell Function and InteractionCAR-T cell therapy research

Cited by 104

Evidence for a novel anti-apoptotic pathway in human keratinocytes involving the aryl hydrocarbon receptor, E2F1, and checkpoint kinase 1

Frauenstein, K., Sydlik, U., Tigges, J., Majora, M., Wiek, C., Hanenberg, H., Abel, J., Esser, C., Fritsche, E., Krutmann, J., et al. (2013) · Cell Death & Differentiation

Skin Protection and AgingCell death mechanisms and regulation

Cited by 56

Profiling the 3D interaction between germ cell tumors and microenvironmental cells at the transcriptome and secretome level

Skowron, M. A., Eul, K., Stephan, A., Ludwig, G. F., Wakileh, G. A., Bister, A., Söhngen, C., Raba, K., Petzsch, P., Poschmann, G., et al. (2022) · Molecular Oncology

Testicular diseases and treatmentsCancer Cells and Metastasis

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