Bottino, Rita

Single-Cell Analysis of Human Pancreas Reveals Transcriptional Signatures of Aging and Somatic Mutation Patterns

Enge, M., Arda, H. E., Mignardi, M., Beausang, J., Bottino, R., Kim, S. K., & Quake, S. R. (2017) · Cell

Single-cell and spatial transcriptomicsPancreatic function and diabetes

Cited by 568

Polycomb protein Ezh2 regulates pancreatic β-cell Ink4a/Arf expression and regeneration in diabetes mellitus

Chen, H., Gu, X., Su, I.-H., Bottino, R., Contreras, J. L., Tarakhovsky, A., & Kim, S. K. (2009) · Genes & Development

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 366

PDGF signalling controls age-dependent proliferation in pancreatic β-cells

Chen, H., Gu, X., Liu, Y., Wang, J., Wirt, S. E., Bottino, R., Schorle, H., Sage, J., & Kim, S. K. (2011) · Nature

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 278

Single-nucleus and in situ RNA-sequencing reveal cell topographies in the human pancreas

Tosti, L., Hang, Y., Debnath, O., Tiesmeyer, S., Trefzer, T., Steiger, K., Ten, F. W., Lukassen, S., Ballke, S., Kühl, A. A., et al. (2021) · Gastroenterology

Single-cell and spatial transcriptomicsPancreatic function and diabetes

Cited by 228

Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function

Arda, H. E., Li, L., Tsai, J., Torre, E. A., Rosli, Y., Peiris, H., Spitale, R. C., Dai, C., Gu, X., Qu, K., et al. (2016) · Cell Metabolism

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 222

The Future of Islet Transplantation Is Now

Bottino, R., Knoll, M. F., Knoll, C. A., Bertera, S., & Trucco, M. M. (2018) · Frontiers in Medicine

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 93