Taketo, Makoto M.

Wnt/β-catenin signaling controls development of the blood–brain barrier

Liebner, S., Corada, M., Bangsow, T., Babbage, J., Taddei, A., Czupalla, C. J., Reis, M., Felici, A., Wolburg, H., Fruttiger, M., et al. (2008) · The Journal of Cell Biology

Barrier Structure and Function StudiesDrug Transport and Resistance Mechanisms

Cited by 860

Hemoprotein Bach1 regulates enhancer availability of heme oxygenase‐1 gene

Sun, J., Hoshino, H., Takaku, K., Nakajima, O., Muto, A., Suzuki, H., Tashiro, S., Takahashi, S., Shibahara, S., Alam, J., et al. (2002) · The EMBO Journal

Heme Oxygenase-1 and Carbon MonoxideGenomics, phytochemicals, and oxidative stress

Cited by 637

HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the β-catenin–TCF interaction

Ye, F., Chen, Y., Hoang, T., Montgomery, R. L., Zhao, X.-H., Bu, H., Hu, T., Taketo, M. M., van Es, J. H., Clevers, H., et al. (2009) · Nature Neuroscience

Neurogenesis and neuroplasticity mechanismsWnt/β-catenin signaling in development and cancer

Cited by 559

Early Embryonic Lethality Caused by Targeted Disruption of the Mouse Thioredoxin Gene

Matsui, M., Oshima, M., Oshima, H., Takaku, K., Maruyama, T., Yodoi, J., & Taketo, M. M. (1996) · Developmental Biology

Redox biology and oxidative stressDevelopmental Biology and Gene Regulation

Cited by 546

Berberine and Its More Biologically Available Derivative, Dihydroberberine, Inhibit Mitochondrial Respiratory Complex I

Turner, N., Li, J.-Y., Gosby, A., To, S. W. C., Cheng, Z., Miyoshi, H., Taketo, M. M., Cooney, G. J., Kraegen, E. W., James, D. E., et al. (2008) · Diabetes

Berberine and alkaloids researchMetabolism, Diabetes, and Cancer

Cited by 535

Gut microbiota promotes obesity-associated liver cancer through pge2-mediated suppression of antitumor immunity.

Loo, T. M., Kamachi, F., Watanabe, Y., Yoshimoto, S., Kanda, H., Arai, Y., Nakajima-Takagi, Y., Iwama, A., Koga, T., Sugimoto, Y., et al. (2017) · Cancer Discovery

Gut microbiota and healthHepatocellular Carcinoma Treatment and Prognosis

Cited by 478

β-catenin activation is necessary and sufficient to specify the dorsal dermal fate in the mouse

Atit, R., Sgaier, S. K., Mohamed, O. A., Taketo, M. M., Dufort, D., Joyner, A. L., Niswander, L., & Conlon, R. A. (2006) · Developmental Biology

Developmental Biology and Gene RegulationWnt/β-catenin signaling in development and cancer

Cited by 400

Apc modulates embryonic stem-cell differentiation by controlling the dosage of β-catenin signaling

Kielman, M. F., Rindapää, M., Gaspar, C., van Poppel, N., Breukel, C., van Leeuwen, S., Taketo, M. M., Roberts, S., Smits, R., & Fodde, R. (2002) · Nature Genetics

Wnt/β-catenin signaling in development and cancerPluripotent Stem Cells Research

Cited by 362

Wnt antagonism of Shh facilitates midbrain floor plate neurogenesis

Joksimovic, M., Yun, B. A., Kittappa, R., Anderegg, A. M., Chang, W. W., Taketo, M. M., McKay, R. D. G., & Awatramani, R. B. (2009) · Nature Neuroscience

Neurogenesis and neuroplasticity mechanismsHedgehog Signaling Pathway Studies

Cited by 213

β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis

Beyer, C., Schramm, A., Akhmetshina, A., Dees, C., Kireva, T., Gelse, K., Sonnylal, S., de Crombrugghe, B., Taketo, M. M., Distler, O., et al. (2012) · Annals of the Rheumatic Diseases

Systemic Sclerosis and Related DiseasesTGF-β signaling in diseases

Cited by 203

Prospero-related homeobox 1 gene (Prox1) is regulated by canonical Wnt signaling and has a stage-specific role in adult hippocampal neurogenesis

Karalay, Ö., Doberauer, K., Vadodaria, K. C., Knobloch, M., Berti, L., Miquelajauregui, A., Schwark, M., Jagasia, R., Taketo, M. M., Tarabykin, V., et al. (2011) · Proceedings of the National Academy of Sciences

Neurogenesis and neuroplasticity mechanismsWnt/β-catenin signaling in development and cancer

Cited by 201

β-catenin mediates glandular formation and dysregulation of β-catenin induces hyperplasia formation in the murine uterus

Jeong, J.-W., Lee, H. S., Franco, H. L., Broaddus, R. R., Taketo, M. M., Tsai, S. Y., Lydon, J. P., & DeMayo, F. J. (2009) · Oncogene

Wnt/β-catenin signaling in development and cancerEndometrial and Cervical Cancer Treatments

Cited by 196

Wnt4/β−Catenin Signaling in Medullary Kidney Myofibroblasts

DiRocco, D. P., Kobayashi, A., Taketo, M. M., McMahon, A. P., & Humphreys, B. D. (2013) · Journal of the American Society of Nephrology

Renal and related cancersWnt/β-catenin signaling in development and cancer

Cited by 173

Endothelial Wnt/β-catenin signaling inhibits glioma angiogenesis and normalizes tumor blood vessels by inducing PDGF-B expression

Reis, M., Czupalla, C. J., Ziegler, N., Devraj, K., Zinke, J., Seidel, S., Heck, R., Thom, S., Macas, J., Bockamp, E., et al. (2012) · Journal of Experimental Medicine

Angiogenesis and VEGF in CancerBarrier Structure and Function Studies

Cited by 167

Chromosomal instability by β-catenin/TCF transcription in APC or β-catenin mutant cells

Aoki, K., Aoki, M., Sugai, M., Harada, N., Miyoshi, H., Tsukamoto, T., Mizoshita, T., Tatematsu, M., Seno, H., Chiba, T., et al. (2007) · Oncogene

Wnt/β-catenin signaling in development and cancerGenetic factors in colorectal cancer

Cited by 82

TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme

Aydoğdu, N., Rudat, C., Trowe, M.-O., Kaiser, M., Lüdtke, T. H., Taketo, M. M., Christoffels, V. M., Moon, A., & Kispert, A. (2018) · Development

Renal and related cancersDevelopmental Biology and Gene Regulation

Cited by 41

Dual blockade of macropinocytosis and asparagine bioavailability shows synergistic anti-tumor effects on KRAS-mutant colorectal cancer

Hanada, K., Kawada, K., Nishikawa, G., Toda, K., Maekawa, H., Nishikawa, Y., Masui, H., Hirata, W., Okamoto, M., Kiyasu, Y., et al. (2021) · Cancer Letters

Cellular transport and secretionProtein Kinase Regulation and GTPase Signaling

Cited by 27