Keedy, Daniel A.

MolProbity : all-atom structure validation for macromolecular crystallography

Chen, V. B., Arendall, W. B., Headd, J. J., Keedy, D. A., Immormino, R. M., Kapral, G. J., Murray, L. W., Richardson, J. S., & Richardson, D. C. (2010) · Acta Crystallographica Section D Biological Crystallography

Enzyme Structure and FunctionProtein Structure and Dynamics

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MolProbity: More and better reference data for improved all‐atom structure validation

Williams, C. J., Headd, J. J., Moriarty, N. W., Prisant, M. G., Videau, L. L., Deis, L. N., Verma, V., Keedy, D. A., Hintze, B. J., Chen, V. B., et al. (2018) · Protein Science

Enzyme Structure and FunctionProtein Structure and Dynamics

Cited by 4,599

Room-temperature crystallography reveals altered binding of small-molecule fragments to PTP1B

Mehlman, T. (., Biel, J. T., Azeem, S. M., Nelson, E. R., Hossain, S., Dunnett, L. E., Paterson, N. G., Douangamath, A., Talon, R., Axford, D., et al. (2022) · eLife

Enzyme Structure and FunctionProtein Tyrosine Phosphatases

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Room-temperature crystallography reveals altered binding of small-molecule fragments to PTP1B

Skaist Mehlman, T., Biel, J. T., Azeem, S. M., Nelson, E. R., Hossain, S., Dunnett, L., Paterson, N. G., Douangamath, A., Talon, R., Axford, D., et al. (2023) · eLife

Enzyme Structure and FunctionProtein Tyrosine Phosphatases

Cited by 84

Automated multiconformer model building for X-ray crystallography and cryo-EM

Wankowicz, S. A., Ravikumar, A., Sharma, S., Riley, B., Raju, A., Hogan, D. W., Flowers, J., van den Bedem, H., Keedy, D. A., & Fraser, J. S. (2024) · eLife

Enzyme Structure and FunctionProtein Structure and Dynamics

Cited by 28

An expanded trove of fragment-bound structures for the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data

Mehlman, T., Ginn, H. M., & Keedy, D. A. (2024) · Structure

Enzyme Structure and FunctionProtein Tyrosine Phosphatases

Cited by 14

An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data

(Skaist) Mehlman, T., Ginn, H. M., & Keedy, D. A. (2024) · Structure

Enzyme Structure and FunctionProtein Tyrosine Phosphatases

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Three STEPs forward: A trio of unexpected structures of PTPN5

Guerrero, L., Ebrahim, A., Riley, B. T., Kim, S. H., Bishop, A. C., Wu, J., Han, Y. N., Tautz, L., & Keedy, D. A. (2024) · Proteins Structure Function and Bioinformatics

Protein Tyrosine PhosphatasesEnzyme Structure and Function

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