Chang, Leifu

Molecular mechanism of APC/C activation by mitotic phosphorylation

Zhang, S., Chang, L., Alfieri, C., Zhang, Z., Yang, J., Maslen, S., Skehel, M., & Barford, D. (2016) · Nature

Microtubule and mitosis dynamicsUbiquitin and proteasome pathways

Cited by 203

Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1

Chen, Q., Plasencia, M., Li, Z., Mukherjee, S., Patra, D., Chen, C.-L., Klose, T., Yao, X.-Q., Kossiakoff, A. A., Chang, L., et al. (2021) · Nature

Receptor Mechanisms and SignalingProtein Kinase Regulation and GTPase Signaling

Cited by 152

Structure of the DOCK2−ELMO1 complex provides insights into regulation of the auto-inhibited state

Chang, L., Yang, J., Jo, C. H., Boland, A., Zhang, Z., McLaughlin, S. H., Abu-Thuraia, A., Killoran, R. C., Smith, M. J., Côté, J.-F., et al. (2020) · Nature Communications

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

Cited by 59

Cryo-EM structures of apo-APC/C and APC/CCDH1:EMI1 complexes provide insights into APC/C regulation

Höfler, A., Yu, J., Yang, J., Zhang, Z., Chang, L., McLaughlin, S. H., Grime, G. W., Garman, E. F., Boland, A., & Barford, D. (2024) · Nature Communications

Microtubule and mitosis dynamicsUbiquitin and proteasome pathways

Cited by 18

New structural features of the APC/C revealed by high resolution cryo-EM structures of apo-APC/C and the APC/CCDH1:EMI1 complex

Barford, D., Höfler, A., Yu, J., Yan, J., Zhang, Z., Chang, L., Grime, G., Garman, E., & Boland, A. (2023) · Nature Communications

Microtubule and mitosis dynamicsUbiquitin and proteasome pathways

Cited by 18