Zuk, Or

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

Guttman, M., Amit, I., Garber, M., French, C., Lin, M. F., Feldser, D., Huarte, M., Zuk, O., Carey, B. W., Cassady, J. P., et al. (2009) · Nature

Cancer-related molecular mechanisms researchGenomics and Chromatin Dynamics

Cited by 4,098

A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response

Huarte, M., Guttman, M., Feldser, D., Garber, M., Koziol, M. J., Kenzelmann-Broz, D., Khalil, A. M., Zuk, O., Amit, I., Rabani, M., et al. (2010) · Cell

Cancer-related molecular mechanisms researchCancer-related Molecular Pathways

Cited by 2,053

The mystery of missing heritability: Genetic interactions create phantom heritability

Zuk, O., Hechter, E., Sunyaev, S. R., & Lander, E. S. (2012) · Proceedings of the National Academy of Sciences

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 1,542

A high-resolution map of human evolutionary constraint using 29 mammals

Broad Institute Sequencing Platform and Whole Genome Assembly Team, Lindblad-Toh, K., Baylor College of Medicine Human Genome Sequencing Center Sequencing Team, Genome Institute at Washington University, Garber, M., Zuk, O., Lin, M. F., Parker, B. J., Washietl, S., Kheradpour, P., et al. (2011) · Nature

Genomics and Phylogenetic StudiesChromosomal and Genetic Variations

Cited by 1,108

Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

Do, R., Stitziel, N. O., Won, H.-H., Jørgensen, A. B., Duga, S., Angelica Merlini, P., Kiezun, A., Farrall, M., Goel, A., Zuk, O., et al. (2015) · Nature

Lipoproteins and Cardiovascular HealthGenetic Associations and Epidemiology

Cited by 650

Searching for missing heritability: Designing rare variant association studies

Zuk, O., Schaffner, S. F., Samocha, K., Do, R., Hechter, E., Kathiresan, S., Daly, M. J., Neale, B. M., Sunyaev, S. R., & Lander, E. S. (2014) · Proceedings of the National Academy of Sciences

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 635

A Composite of Multiple Signals Distinguishes Causal Variants in Regions of Positive Selection

Grossman, S. R., Shylakhter, I., Karlsson, E. K., Byrne, E. H., Morales, S., Frieden, G., Hostetter, E., Angelino, E., Garber, M., Zuk, O., et al. (2010) · Science

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 512

Unbiased Reconstruction of a Mammalian Transcriptional Network Mediating Pathogen Responses

Amit, I., Garber, M., Chevrier, N., Leite, A. P., Donner, Y., Eisenhaure, T., Guttman, M., Grenier, J. K., Li, W., Zuk, O., et al. (2009) · Science

Gene Regulatory Network AnalysisGenomics and Chromatin Dynamics

Cited by 488

Conservation and divergence in the transcriptional programs of the human and mouse immune systems

Shay, T., Jojic, V., Zuk, O., Rothamel, K., Puyraimond-Zemmour, D., Feng, T., Wakamatsu, E., Benoist, C., Koller, D., Regev, A., et al. (2013) · Proceedings of the National Academy of Sciences

Genomics and Chromatin DynamicsBioinformatics and Genomic Networks

Cited by 359

ImmGen report: sexual dimorphism in the immune system transcriptome

Gal-Oz, S. T., Maier, B., Yoshida, H., Seddu, K., Elbaz, N., Czysz, C., Zuk, O., Stranger, B. E., Ner-Gaon, H., & Shay, T. (2019) · Nature Communications

Sex and Gender in HealthcareGenetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

Cited by 274

Sorting points into neighborhoods (SPIN): data analysis and visualization by ordering distance matrices

Tsafrir, D., Tsafrir, I., Ein-Dor, L., Zuk, O., Notterman, D. A., & Domany, E. (2005) · Bioinformatics

Gene expression and cancer classificationTopological and Geometric Data Analysis

Cited by 146

Screening Human Embryos for Polygenic Traits Has Limited Utility

Karavani, E., Zuk, O., Zeevi, D., Barzilai, N., Stefanis, N. C., Hatzimanolis, A., Smyrnis, N., Avramopoulos, D., Kruglyak, L., Atzmon, G., et al. (2019) · Cell

Prenatal Screening and DiagnosticsAssisted Reproductive Technology and Twin Pregnancy

Cited by 111

The promoters of human cell cycle genes integrate signals from two tumor suppressive pathways during cellular transformation

Tabach, Y., Milyavsky, M., Shats, I., Brosh, R., Zuk, O., Yitzhaky, A., Mantovani, R., Domany, E., Rotter, V., & Pilpel, Y. (2005) · Molecular Systems Biology

Cancer-related Molecular PathwaysGenomics and Chromatin Dynamics

Cited by 72