Gaulton, Kyle J.

The genetic architecture of type 2 diabetes

Fuchsberger, C., Flannick, J., Teslovich, T. M., Mahajan, A., Agarwala, V., Gaulton, K. J., Ma, C., Fontanillas, P., Moutsianas, L., McCarthy, D. J., et al. (2016) · Nature

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 1,051

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Mahajan, A., Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium, South Asian Type 2 Diabetes (SAT2D) Consortium, Mexican American Type 2 Diabetes (MAT2D) Consortium, Type 2 Diabetes Genetic Exploration by Next-generation sequencing in multi-Ethnic Samples (T2D-GENES) Consortium, Go, M. J., Zhang, W., Below, J. E., Gaulton, K. J., et al. (2014) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 1,034

Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

Mahajan, A., Spracklen, C. N., Zhang, W., Ng, M. C. Y., Petty, L. E., Kitajima, H., Yu, G. Z., Rüeger, S., Speidel, L., Kim, Y. J., et al. (2022) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 704

Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: a soft clustering analysis

Udler, M. S., Kim, J., von Grotthuss, M., Bonàs-Guarch, S., Cole, J. B., Chiou, J., ISGC, C. D. A. O. B. O. M. A. T., Boehnke, M., Laakso, M., Atzmon, G., et al. (2018) · PLOS Medicine

Genetic Associations and EpidemiologyDiabetes and associated disorders

Cited by 542

A single-cell atlas of chromatin accessibility in the human genome

Zhang, K., Hocker, J. D., Miller, M., Hou, X., Chiou, J., Poirion, O. B., Qiu, Y., Li, Y. E., Gaulton, K. J., Wang, A., et al. (2021) · Cell

Genomics and Chromatin DynamicsSingle-cell and spatial transcriptomics

Cited by 502

Detection of human adaptation during the past 2000 years

Field, Y., Boyle, E. A., Telis, N., Gao, Z., Gaulton, K. J., Golan, D., Yengo, L., Rocheleau, G., Froguel, P., McCarthy, M. I., et al. (2016) · Science

Forensic and Genetic ResearchEvolution and Genetic Dynamics

Cited by 383

Characterizing cis-regulatory elements using single-cell epigenomics

Preissl, S., Gaulton, K. J., & Ren, B. (2023) · Nature Reviews Genetics

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 251

Single cell chromatin accessibility reveals pancreatic islet cell type- and state-specific regulatory programs of diabetes risk

Chiou, J., Zeng, C., Cheng, Z., Han, J. Y., Schlichting, M., Huang, S., Wang, J., Sui, Y., Deogaygay, A., Okino, M.-L., et al. (2019) · Nature Genetics

Pancreatic function and diabetesGenomics and Chromatin Dynamics

Cited by 189

An atlas of gene regulatory elements in adult mouse cerebrum

Li, Y. E., Preissl, S., Hou, X., Zhang, Z., Zhang, K., Qiu, Y., Poirion, O. B., Li, B., Chiou, J., Liu, H., et al. (2021) · Nature

Genomics and Chromatin DynamicsSingle-cell and spatial transcriptomics

Cited by 185

Identification of a regulatory variant that binds FOXA1 and FOXA2 at the CDC123/CAMK1D type 2 diabetes GWAS locus

Fogarty, M. P., Cannon, M. E., Vadlamudi, S., Gaulton, K. J., & Mohlke, K. L. (2014) · PLoS Genetics

Genetic Associations and EpidemiologyGenomics and Chromatin Dynamics

Cited by 93

Improving stem cell-derived pancreatic islets using single-cell multiome-inferred regulomes

Zhu, H., Wang, G., Nguyen-Ngoc, K.-V., Kim, D., Miller, M., Goss, G., Kovsky, J., Harrington, A. R., Saunders, D., Melton, R., et al. (2022) · Developmental Cell

Pancreatic function and diabetesSingle-cell and spatial transcriptomics

Cited by 85