Kiemer, Alexandra K.

Identification of genes involved in epithelial-mesenchymal transition and tumor progression

Kiemer, A. K., Takeuchi, K., & Quinlan, M. P. (2001) · Oncogene

Cancer Cells and MetastasisTGF-β signaling in diseases

Cited by 77

First Small-Molecule Inhibitors Targeting the RNA-Binding Protein IGF2BP2/IMP2 for Cancer Therapy

Dahlem, C., Abuhaliema, A., Kessler, S. M., Kröhler, T., Zoller, B. G. E., Chanda, S., Wu, Y., Both, S., Müller, F., Lepikhov, K., et al. (2022) · ACS Chemical Biology

RNA Research and SplicingCancer Mechanisms and Therapy

Cited by 70

Overexpression of the IGF2-mRNA binding protein p62 in transgenic mice induces a steatotic phenotype

Tybl, E., Shi, F.-D., Kessler, S. M., Tierling, S., Walter, J., Bohle, R. M., Wieland, S., Zhang, J., Tan, E. M., & Kiemer, A. K. (2011) · Journal of Hepatology

Growth Hormone and Insulin-like Growth FactorsGenetic Syndromes and Imprinting

Cited by 65

IGF2 mRNA Binding Protein 2 Transgenic Mice Are More Prone to Develop a Ductular Reaction and to Progress Toward Cirrhosis

Czepukojc, B., Abuhaliema, A., Barghash, A., Tierling, S., Naß, N., Simon, Y., Körbel, C., Cadenas, C., van Hul, N., Sachinidis, A., et al. (2019) · Frontiers in Medicine

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 20

The RNA binding protein IGF2BP2/IMP2 alters the cargo of cancer cell-derived extracellular vesicles supporting tumor-associated macrophages

Mashayekhi, V., Schomisch, A., Rasheed, S., Aparicio-Puerta, E., Risch, T., Yildiz, D., Koch, M., Both, S., Ludwig, N., Legroux, T. M., et al. (2024) · Cell Communication and Signaling

Extracellular vesicles in diseaseImmune cells in cancer

Cited by 14

Gene Editing and Small Molecule Inhibitors of the RNA Binding Protein IGF2BP2/IMP2 Show its Potential as an Anti-Cancer Drug Target

Chanda, S., Lepikhov, K., Dahlem, C., Schymik, H. S., Hoppstädter, J., Geber, A.-K., Wagner, K., Kessler, S. M., Empting, M., & Kiemer, A. K. (2024) · Frontiers in Bioscience-Landmark

RNA Research and SplicingRNA regulation and disease

Cited by 8