Laurent, Didier

Effects of free fatty acids on glucose transport and IRS-1–associated phosphatidylinositol 3-kinase activity

Dresner, A., Laurent, D., Marcucci, M., Griffin, M. E., Dufour, S., Cline, G. W., Slezak, L. A., Andersen, D. K., Hundal, R. S., Rothman, D. L., et al. (1999) · Journal of Clinical Investigation

Metabolism, Diabetes, and CancerDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 1,311

Mechanism by which metformin reduces glucose production in type 2 diabetes.

Hundal, R. S., Krssak, M., Dufour, S., Laurent, D., Lebon, V, Chandramouli, V, Inzucchi, S. E., Schumann, W. C., Petersen, K. F., Landau, B. R., et al. (2000) · Diabetes

Metabolism, Diabetes, and CancerDiabetes Treatment and Management

Cited by 1,052

Effect of Bimagrumab vs Placebo on Body Fat Mass Among Adults With Type 2 Diabetes and Obesity: A Phase 2 Randomized Clinical Trial

Heymsfield, S. B., Coleman, L. A., Miller, R., Rooks, D. S., Laurent, D., Petricoul, O., Praestgaard, J., Swan, T., Wade, T., Perry, R. G., et al. (2021) · JAMA Network Open

Adipokines, Inflammation, and Metabolic DiseasesDiabetes Treatment and Management

Cited by 338

Treatment of Sarcopenia with Bimagrumab: Results from a Phase II, Randomized, Controlled, Proof‐of‐Concept Study

Rooks, D., Praestgaard, J., Hariry, S., Laurent, D., Petricoul, O., Perry, R. G., Lach‐Trifilieff, E., & Roubenoff, R. (2017) · Journal of the American Geriatrics Society

Nutrition and Health in AgingMuscle Physiology and Disorders

Cited by 244

Treatment of sporadic inclusion body myositis with bimagrumab

Amato, A. A., Sivakumar, K., Goyal, N., David, W. S., Salajegheh, M., Praestgaard, J., Lach-Trifilieff, E., Trendelenburg, A.-U., Laurent, D., Glass, D. J., et al. (2014) · Neurology

Inflammatory Myopathies and DermatomyositisMuscle Physiology and Disorders

Cited by 210

Bimagrumab vs Optimized Standard of Care for Treatment of Sarcopenia in Community-Dwelling Older Adults: A Randomized Clinical Trial

Rooks, D., Swan, T., Goswami, B., Filosa, L. A., Bunte, O., Panchaud, N., Coleman, L. A., Miller, R. R., Garcia Garayoa, E., Praestgaard, J., et al. (2020) · JAMA Network Open

Nutrition and Health in AgingMuscle Physiology and Disorders

Cited by 177

Effect of bimagrumab on thigh muscle volume and composition in men with casting‐induced atrophy

Rooks, D. S., Laurent, D., Praestgaard, J., Rasmussen, S., Bartlett, M., & Tankó, L. B. (2017) · Journal of Cachexia, Sarcopenia and Muscle

Muscle Physiology and DisordersNutrition and Health in Aging

Cited by 90

Bimagrumab improves body composition and insulin sensitivity in insulin‐resistant individuals

Garito, T., Roubenoff, R., Hompesch, M., Morrow, L., Gomez, K., Rooks, D., Meyers, C., Buchsbaum, M. S., Neelakantham, S., Swan, T., et al. (2018) · Diabetes, Obesity and Metabolism

Adipokines, Inflammation, and Metabolic DiseasesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 88

Safety and pharmacokinetics of bimagrumab in healthy older and obese adults with body composition changes in the older cohort

Rooks, D., Petricoul, O., Praestgaard, J., Bartlett, M., Laurent, D., & Roubenoff, R. (2020) · Journal of Cachexia, Sarcopenia and Muscle

Muscle Physiology and DisordersNutrition and Health in Aging

Cited by 54

Effects of bimagrumab, an activin receptor type II inhibitor, on pituitary neurohormonal axes

Garito, T., Zakaria, M., Papanicolaou, D. A., Li, Y., Pinot, P., Petricoul, O., Laurent, D., Rooks, D., Rondon, J. C., & Roubenoff, R. (2018) · Clinical Endocrinology

Adrenal Hormones and DisordersHypothalamic control of reproductive hormones

Cited by 31