Kempf, Georg

Structural mechanism of cGAS inhibition by the nucleosome

Pathare, G. R., Decout, A., Glück, S., Cavadini, S., Makasheva, K., Hovius, R., Kempf, G., Weiss, J., Kozicka, Z., Guey, B., et al. (2020) · Nature

interferon and immune responsesDNA and Nucleic Acid Chemistry

Cited by 273

Design principles for cyclin K molecular glue degraders

Kozicka, Z., Suchyta, D. J., Focht, V., Kempf, G., Petzold, G., Jentzsch, M., Zou, C., Di Genua, C., Donovan, K. A., Coomar, S., et al. (2024) · Nature Chemical Biology

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 113

UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability

Tsai, J. M., Aguirre, J. D., Li, Y.-D., Brown, J., Focht, V., Kater, L., Kempf, G., Sandoval, B., Schmitt, S., Rutter, J. C., et al. (2023) · Molecular Cell

Estrogen and related hormone effectsUbiquitin and proteasome pathways

Cited by 68

The genetic architecture of protein interaction affinity and specificity

Bendel, A. M., Faure, A. J., Klein, D., Shimada, K., Lyautey, R., Schiffelholz, N., Kempf, G., Cavadini, S., Lehner, B., & Diss, G. (2024) · Nature Communications

Protein Structure and DynamicsEvolution and Genetic Dynamics

Cited by 22

The genetic architecture of protein interaction affinity and specificity

Bendel, A. M., Faure, A. J., Klein, D., Shimada, K., Kempf, G., Cavadini, S., Lehner, B., & Diss, G. (2023) · Nature Communications

Protein Structure and DynamicsEvolution and Genetic Dynamics

Cited by 22