Lee, Seong Won

Striatal neurons directly converted from Huntington’s disease patient fibroblasts recapitulate age-associated disease phenotypes

Victor, M. B., Richner, M., Olsen, H. E., Lee, S. W., Monteys, A. M., Ma, C., Huh, C. J., Zhang, B., Davidson, B. L., Yang, X. W., et al. (2018) · Nature Neuroscience

Genetic Neurodegenerative DiseasesPluripotent Stem Cells Research

Cited by 246

MicroRNAs Induce a Permissive Chromatin Environment that Enables Neuronal Subtype-Specific Reprogramming of Adult Human Fibroblasts

Abernathy, D. G., Kim, W. K., McCoy, M. J., Lake, A. M., Ouwenga, R., Lee, S. W., Xing, X., Li, D., Lee, H. J., Heuckeroth, R. O., et al. (2017) · Cell Stem Cell

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 145

Age-related Huntington’s disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy

Oh, Y. M., Lee, S. W., Kim, W. K., Chen, S., Church, V. A., Cates, K., Li, T., Zhang, B., Dolle, R. E., Dahiya, S., et al. (2022) · Nature Neuroscience

Genetic Neurodegenerative DiseasesAutophagy in Disease and Therapy

Cited by 100