Rynn, Caroline
Novartis Institutes for BioMedical Research
2 papers on CoChatORCID 0000-0002-7616-3872
Most cited papers
- Verified
Discovery of a Dihydroisoquinolinone Derivative (NVP-CGM097): A Highly Potent and Selective MDM2 Inhibitor Undergoing Phase 1 Clinical Trials in p53wt Tumors
Holzer, P., Masuya, K., Furet, P., Kallen, J., Valat-Stachyra, T., Ferretti, S., Berghausen, J., Bouisset-Leonard, M., Buschmann, N., Pissot-Soldermann, C., et al. (2015) · Journal of Medicinal Chemistry
Cancer-related Molecular PathwaysCancer Mechanisms and Therapy
Cited by 203
- Verified
A distinct p53 target gene set predicts for response to the selective p53–HDM2 inhibitor NVP-CGM097
Jeay, S., Gaulis, S., Ferretti, S., Bitter, H., Ito, M., Valat, T., Murakami, M., Ruetz, S., Guthy, D. A., Rynn, C., et al. (2015) · eLife
Cancer-related Molecular PathwaysPI3K/AKT/mTOR signaling in cancer
Cited by 85
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