Selak, Mary A.

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-α prolyl hydroxylase

Selak, M. A., Armour, S. M., MacKenzie, E. D., Boulahbel, H., Watson, D. G., Mansfield, K. D., Pan, Y., Simon, M. C., Thompson, C. B., & Gottlieb, E. (2005) · Cancer Cell

Cancer, Hypoxia, and MetabolismEar and Head Tumors

Cited by 2,108

TIGAR, a p53-Inducible Regulator of Glycolysis and Apoptosis

Bensaad, K., Tsuruta, A., Selak, M. A., Vidal, M. N. C., Nakano, K., Bartrons, R., Gottlieb, E., & Vousden, K. H. (2006) · Cell

Cancer-related Molecular PathwaysCancer, Hypoxia, and Metabolism

Cited by 2,019

Chemotherapy-Resistant Human Acute Myeloid Leukemia Cells Are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism

Farge, T., Saland, E., de Toni, F., Aroua, N., Hosseini, M., Perry, R., Bosc, C., Sugita, M., Stuani, L., Fraisse, M., et al. (2017) · Cancer Discovery

Acute Myeloid Leukemia ResearchCancer, Hypoxia, and Metabolism

Cited by 912

Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer

King, A., Selak, M. A., & Gottlieb, E. (2006) · Oncogene

Cancer, Hypoxia, and MetabolismMitochondrial Function and Pathology

Cited by 672

Cell-Permeating α -Ketoglutarate Derivatives Alleviate Pseudohypoxia in Succinate Dehydrogenase-Deficient Cells

MacKenzie, E. D., Selak, M. A., Tennant, D. A., Payne, L. J., Crosby, S., Frederiksen, C. M., Watson, D. G., & Gottlieb, E. (2007) · Molecular and Cellular Biology

Cancer, Hypoxia, and MetabolismBiochemical Acid Research Studies

Cited by 359

Hypoxia-inducible factor 2 regulates hepatic lipid metabolism

Rankin, E. B., Rha, J., Selak, M. A., Unger, T. L., Keith, B., Liu, Q., & Haase, V. H. (2009) · Molecular and Cellular Biology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 338

Progressive accumulation of mitochondrial DNA mutations and decline in mitochondrial function lead to β-cell failure.

Simmons, R. A., Suponitsky-Kroyter, I., & Selak, M. A. (2005) · Journal of Biological Chemistry

Pancreatic function and diabetesMitochondrial Function and Pathology

Cited by 194

Distribution of oligodendrocyte loss and mitochondrial toxicity in the cuprizone-induced experimental demyelination model

Acs, P., Selak, M. A., Komoly, S., & Kalman, B. (2013) · Journal of Neuroimmunology

Mitochondrial Function and PathologyMultiple Sclerosis Research Studies

Cited by 84

Redox stress is not essential for the pseudo-hypoxic phenotype of succinate dehydrogenase deficient cells

Selak, M. A., Durán, R. V., & Gottlieb, E. (2006) · Biochimica et Biophysica Acta (BBA) - Bioenergetics

Cancer, Hypoxia, and MetabolismFerroptosis and cancer prognosis

Cited by 59