Medvedovic, Mario

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations

Keenan, A. B., Jenkins, S. L., Jagodnik, K. M., Koplev, S., He, E., Torre, D., Wang, Z., Dohlman, A. B., Silverstein, M. C., Lachmann, A., et al. (2018) · Cell Systems

Bioinformatics and Genomic NetworksGene Regulatory Network Analysis

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Intensity-based hierarchical bayes method improves testing for differentially expressed genes in microarray experiments

Sartor, M. A., Tomlinson, C. R., Wesselkamper, S. C., Sivaganesan, S., Leikauf, G. D., & Medvedovic, M. (2006) · BMC Bioinformatics

Gene expression and cancer classificationBioinformatics and Genomic Networks

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Data Portal for the Library of Integrated Network-based cellular Signatures (LINCS) program: integrated access to diverse large-scale cellular perturbation response data

Koleti, A., Terryn, R., Stathias, V., Chung, C., Cooper, D. J., Turner, J. P., Vidović, D., Forlin, M., Kelley, T. T., D’Urso, A., et al. (2018) · Nucleic Acids Research

Bioinformatics and Genomic NetworksResearch Data Management Practices

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LINCS Data Portal 2.0: next generation access point for perturbation-response signatures

Stathias, V., Turner, J., Koleti, A., Vidovic, D., Cooper, D., Fazel-Najafabadi, M., Pilarczyk, M., Terryn, R., Chung, C., Umeano, A., et al. (2020) · Nucleic Acids Research

Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies

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A Multi-center Study on the Reproducibility of Drug-Response Assays in Mammalian Cell Lines

Niepel, M., Hafner, M., Mills, C. E., Subramanian, K., Williams, E. H., Chung, M., Gaudio, B., Barrette, A. M., Stern, A. D., Hu, B., et al. (2019) · Cell Systems

Scientific Computing and Data ManagementAnimal testing and alternatives

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GRcalculator: an online tool for calculating and mining dose–response data

Clark, N. A., Hafner, M., Kouril, M., Williams, E. H., Muhlich, J. L., Pilarczyk, M., Niepel, M., Sorger, P. K., & Medvedovic, M. (2017) · BMC Cancer

Computational Drug Discovery MethodsCell Image Analysis Techniques

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Sex- and tissue-specific methylome changes in brains of mice perinatally exposed to lead

Sánchez-Martín, F. J., Lindquist, D. M., Landero-Figueroa, J., Zhang, X., Chen, J., Cecil, K. M., Medvedovic, M., & Puga, A. (2015) · NeuroToxicology

Heavy Metal Exposure and ToxicityEpigenetics and DNA Methylation

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Differences in peripheral immune system gene expression in frontotemporal degeneration

Sawyer, R. P., Hill, E. J., Yokoyama, J., Medvedovic, M., Ren, Y., Zhang, X., Choubey, D., Shatz, R. S., Miller, B., & Woo, D. (2022) · Medicine

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

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