Therrien, Marc

ERK signalling: A master regulator of cell behaviour, life and fate

Lavoie, H., Gagnon, J., & Therrien, M. (2020) · Nature Reviews Molecular Cell Biology

Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways

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Inhibition of RAS function through targeting an allosteric regulatory site

Spencer-Smith, R., Koide, A., Zhou, Y., Eguchi, R. R., Sha, F., Gajwani, P., Santana, D., Gupta, A., Jacobs, M., Herrero-Garcia, E., et al. (2017) · Nature Chemical Biology

Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways

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KSR modulates signal propagation within the MAPK cascade.

Therrien, M., Michaud, N. R., Rubin, G. M., & Morrison, D. K. (1996) · Genes & Development

Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways

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KSR is a scaffold required for activation of the ERK/MAPK module

Roy, F., Laberge, G., Douziech, M., Ferland-McCollough, D., & Therrien, M. (2002) · Genes & Development

Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways

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