Shinkai, Yoichi

SET Domain-containing Protein, G9a, Is a Novel Lysine-preferring Mammalian Histone Methyltransferase with Hyperactivity and Specific Selectivity to Lysines 9 and 27 of Histone H3

Tachibana, M., Sugimoto, K., Fukushima, T., & Shinkai, Y. (2001) · Journal of Biological Chemistry

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 784

G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis

Feldman, N., Gerson, A., Fang, J., Li, E., Zhang, Y., Shinkai, Y., Cedar, H., & Bergman, Y. (2006) · Nature Cell Biology

Epigenetics and DNA MethylationPluripotent Stem Cells Research

Cited by 651

DNA Methylation and SETDB1/H3K9me3 Regulate Predominantly Distinct Sets of Genes, Retroelements, and Chimeric Transcripts in mESCs

Karimi, M. M., Goyal, P., Maksakova, I. A., Bilenky, M., Leung, D., Tang, J. X., Shinkai, Y., Mager, D. L., Jones, S., Hirst, M., et al. (2011) · Cell Stem Cell

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 535

Protein lysine methyltransferase G9a acts on non-histone targets

Rathert, P., Dhayalan, A., Murakami, M., Zhang, X., Tamas, R., Jurkowska, R., Komatsu, Y., Shinkai, Y., Cheng, X., & Jeltsch, A. (2008) · Nature Chemical Biology

Cancer-related gene regulationEpigenetics and DNA Methylation

Cited by 347

DNA Damage Signaling Triggers Degradation of Histone Methyltransferases through APC/CCdh1 in Senescent Cells

Takahashi, A., Imai, Y., Yamakoshi, K., Kuninaka, S., Ohtani, N., Yoshimoto, S., Hori, S., Tachibana, M., Anderton, E., Takeuchi, T., et al. (2012) · Molecular Cell

Telomeres, Telomerase, and SenescenceEpigenetics and DNA Methylation

Cited by 205

Methylation of DNA Ligase 1 by G9a/GLP Recruits UHRF1 to Replicating DNA and Regulates DNA Methylation

Ferry, L., Fournier, A., Tsusaka, T., Adelmant, G., Shimazu, T., Matano, S., Kirsh, O., Amouroux, R., Dohmae, N., Suzuki, T., et al. (2017) · Molecular Cell

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 203

Severe growth defect in mouse cells lacking the telomerase RNA component

Niida, H., Matsumoto, T., Satoh, H., Shiwa, M., Tokutake, Y., Furuichi, Y., & Shinkai, Y. (1998) · Nature Genetics

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 156

DMRT1-mediated reprogramming drives development of cancer resembling human germ cell tumors with features of totipotency

Taguchi, J., Shibata, H., Kabata, M., Kato, M., Fukuda, K., Tanaka, A., Ohta, S., Ukai, T., Mitsunaga, K., Yamada, Y., et al. (2021) · Nature Communications

Pluripotent Stem Cells ResearchGenetic Syndromes and Imprinting

Cited by 46

Prdm8 regulates the morphological transition at multipolar phase during neocortical development

Inoue, M., Kuroda, T., Honda, A., Komabayashi-Suzuki, M., Komai, T., Shinkai, Y., & Mizutani, K.-I. (2014) · PLoS ONE

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 41