Holz, George G.

Epac-selective cAMP Analog 8-pCPT-2′-O-Me-cAMP as a Stimulus for Ca2+-induced Ca2+ Release and Exocytosis in Pancreatic β-Cells

Kang, G., Joseph, J. W., Chepurny, O. G., Monaco, M., Wheeler, M. B., Bos, J. L., Schwede, F., Genieser, H.-G., & Holz, G. G. (2003) · Journal of Biological Chemistry

Pancreatic function and diabetesCalcium signaling and nucleotide metabolism

Cited by 298

Regulation of Glucose Homeostasis by GLP-1

Nadkarni, P., Chepurny, O. G., & Holz, G. G. (2014) · Progress in Molecular Biology and Translational Science

Diabetes Treatment and ManagementPancreatic function and diabetes

Cited by 287

Leptin Suppression of Insulin Secretion and Gene Expression in Human Pancreatic Islets: Implications for the Development of Adipogenic Diabetes Mellitus1

Seufert, J., Kieffer, T. J., Leech, C. A., Holz, G. G., Moritz, W., Ricordi, C., & Habener, J. F. (1999) · The Journal of Clinical Endocrinology & Metabolism

Pancreatic function and diabetesAdipokines, Inflammation, and Metabolic Diseases

Cited by 278

cAMP-dependent Mobilization of Intracellular Ca2+ Stores by Activation of Ryanodine Receptors in Pancreatic β-Cells

Holz, G. G., Leech, C. A., Heller, R. S., Castonguay, M., & Habener, J. F. (1999) · Journal of Biological Chemistry

Pancreatic function and diabetesIon channel regulation and function

Cited by 220

Activation of a cAMP-regulated Ca2+-Signaling Pathway in Pancreatic β-Cells by the Insulinotropic Hormone Glucagon-like Peptide-1

Holz, G. G., Leech, C. A., & Habener, J. F. (1995) · Journal of Biological Chemistry

Pancreatic function and diabetesIon channel regulation and function

Cited by 188

Epac2-Dependent Rap1 Activation and the Control of Islet Insulin Secretion by Glucagon-Like Peptide-1

Leech, C. A., Chepurny, O. G., & Holz, G. G. (2010) · Vitamins & Hormones

Pancreatic function and diabetesProtein Kinase Regulation and GTPase Signaling

Cited by 76

Epac2-dependent mobilization of intracellular Ca2+by glucagon-like peptide-1 receptor agonist exendin-4 is disrupted in β-cells of phospholipase C-ɛ knockout mice: Calcium mobilizing properties of exendin-4 in mouse β-cells

Dzhura, I., Chepurny, O. G., Kelley, G. G., Leech, C. A., Roe, M. W., Dzhura, E., Afshari, P., Malik, S., Rindler, M. J., Xu, X., et al. (2010) · The Journal of Physiology

Pancreatic function and diabetesCalcium signaling and nucleotide metabolism

Cited by 67

Corrination of a GLP-1 Receptor Agonist for Glycemic Control without Emesis

Borner, T., Workinger, J. L., Tinsley, I. C., Fortin, S. M., Stein, L. M., Chepurny, O. G., Holz, G. G., Wierzba, A. J., Gryko, D., Nexø, E., et al. (2020) · Cell Reports

Diabetes Treatment and ManagementDiabetes Management and Research

Cited by 39