Brimacombe, Kyle R
National Institutes of Health · National Center for Advancing Translational Sciences
3 papers on CoChatORCID 0000-0002-9629-1417
Most cited papers
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Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis
Anastasiou, D., Yu, Y., Israelsen, W. J., Jiang, J.-K., Boxer, M. B., Hong, B. S., Tempel, W., Dimov, S., Shen, M., Jha, A., et al. (2012) · Nature Chemical Biology
Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer
Cited by 816
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A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate
Pacold, M. E., Brimacombe, K. R., Chan, S. H., Rohde, J. M., Lewis, C. A., Swier, L. J. Y. M., Possemato, R., Chen, W. W., Sullivan, L. B., Fiske, B. P., et al. (2016) · Nature Chemical Biology
Cancer, Hypoxia, and MetabolismBiochemical and Molecular Research
Cited by 553
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Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo
Najm, F. J., Madhavan, M., Zaremba, A., Shick, E., Karl, R. T., Factor, D. C., Miller, T. E., Nevin, Z. S., Kantor, C., Sargent, A., et al. (2015) · Nature
Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms
Cited by 424
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