Lei, Jianlin

Molecular Architecture of the SARS-CoV-2 Virus

Yao, H., Song, Y., Chen, Y., Wu, N., Xu, J., Sun, C., Zhang, J., Weng, T., Zhang, Z., Wu, Z., et al. (2020) · Cell

SARS-CoV-2 and COVID-19 ResearchAdvanced Electron Microscopy Techniques and Applications

Cited by 1,060

Structure of the human LAT1–4F2hc heteromeric amino acid transporter complex

Yan, R., Zhao, X., Lei, J., & Zhou, Q. (2019) · Nature

Amino Acid Enzymes and MetabolismProtein Structure and Dynamics

Cited by 358

Recognition of the amyloid precursor protein by human γ-secretase

Zhou, R., Yang, G., Guo, X., Zhou, Q., Lei, J., & Shi, Y. (2019) · Science

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 304

Structure of the human PKD1-PKD2 complex

Su, Q., Hu, F., Ge, X., Lei, J., Yu, S., Wang, T., Zhou, Q., Mei, C., & Shi, Y. (2018) · Science

Genetic and Kidney Cyst DiseasesIon Channels and Receptors

Cited by 284

Structural basis for the recognition of Sonic Hedgehog by human Patched1

Gong, X., Qian, H., Cao, P., Zhao, X., Zhou, Q., Lei, J., & Yan, N. (2018) · Science

Hedgehog Signaling Pathway StudiesReceptor Mechanisms and Signaling

Cited by 216

Structural basis of γ-secretase inhibition and modulation by small molecule drugs

Yang, G., Zhou, R., Guo, X., Yan, C., Lei, J., & Shi, Y. (2021) · Cell

Alzheimer's disease research and treatmentsCholinesterase and Neurodegenerative Diseases

Cited by 189

Structural and functional insights into the mode of action of a universally conserved Obg GTPase.

Feng, B., Mandava, C. S., Guo, Q., Wang, J., Cao, W., Li, N., Zhang, Y., Zhang, Y., Wang, Z., Wu, J., et al. (2014) · PLoS Biology

RNA and protein synthesis mechanismsBacterial Genetics and Biotechnology

Cited by 129

A structure of human Scap bound to Insig-2 suggests how their interaction is regulated by sterols

Yan, R., Cao, P., Song, W., Qian, H., Du, X., Coates, H. W., Zhao, X., Li, Y., Gao, S., Gong, X., et al. (2021) · Science

Cholesterol and Lipid MetabolismLipid Membrane Structure and Behavior

Cited by 100

Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S

Guan, H., Wang, P., Zhang, P., Ruan, C., Ou, Y., Peng, B., Zheng, X., Lei, J., Li, B., Yan, C., et al. (2023) · Nature

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 40

Cryo-EM structure of the inner ring from the Xenopus laevis nuclear pore complex

Huang, G., Zhan, X., Zeng, C., Liang, K., Zhu, X., Zhao, Y., Wang, P., Wang, Q., Zhou, Q., Tao, Q., et al. (2022) · Cell Research

Nuclear Structure and FunctionProtein Structure and Dynamics

Cited by 33

Cryo-EM structure of the Inner Ring from Xenopus laevis Nuclear Pore Complex

Huang, G., Zhan, X., Zeng, C., Liang, K., Zhu, X., Zhao, Y., Wang, P., Wang, Q., Zhou, Q., Tao, Q., et al. (2021) · Cell Research

Nuclear Structure and FunctionProtein Structure and Dynamics

Cited by 33

Structural and functional insights of the human peroxisomal ABC transporter ALDP

Jia, Y., Zhang, Y., Wang, W., Lei, J., Ying, Z., & Yang, G. (2022) · eLife

Metabolism and Genetic DisordersDrug Transport and Resistance Mechanisms

Cited by 15

Structure insights of the human peroxisomal ABC transporter ALDP

Jia, Y., Zhang, Y., Lei, J., & Yang, G. (2021) · eLife

Metabolism and Genetic DisordersDrug Transport and Resistance Mechanisms

Cited by 15