Gremer, Lothar

Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo

Ismail, S. A., Chen, Y.-X., Rusinova, A., Chandra, A., Bierbaum, M., Gremer, L., Triola, G., Waldmann, H., Bastiaens, P. I. H., & Wittinghofer, A. (2011) · Nature Chemical Biology

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

Cited by 252

Cryo-EM structure of islet amyloid polypeptide fibrils reveals similarities with amyloid-β fibrils

Röder, C., Kupreichyk, T., Gremer, L., Schäfer, L. U., Pothula, K. R., Ravelli, R. B. G., Willbold, D., Hoyer, W., & Schröder, G. F. (2020) · Nature Structural & Molecular Biology

Alzheimer's disease research and treatmentsPancreatic function and diabetes

Cited by 180

Rho-kinase: Regulation, (dys)function, and inhibition

Amin, E., Dubey, B. N., Zhang, S.-C., Gremer, L., Dvorsky, R., Moll, J. M., Taha, M. S., Nagel-Steger, L., Piekorz, R. P., Somlyo, A. V., et al. (2013) · bchm

Protein Kinase Regulation and GTPase SignalingCellular Mechanics and Interactions

Cited by 176

Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders

Gremer, L., Merbitz-Zahradnik, T., Dvorsky, R., Cirstea, I. C., Kratz, C. P., Zenker, M., Wittinghofer, A., & Ahmadian, M. R. (2011) · Human Mutation

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

Cited by 158

The C2 domain of SynGAP is essential for stimulation of the Rap GTPase reaction

Pena, V., Hothorn, M., Eberth, A., Kaschau, N., Parret, A., Gremer, L., Bonneau, F., Ahmadian, M. R., & Scheffzek, K. (2008) · The EMBO Reports

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

Cited by 101

Mechanistic insights into specificity, activity, and regulatory elements of the regulator of G-protein signaling (RGS)-containing Rho-specific guanine nucleotide exchange factors (GEFs) p115, PDZ-RhoGEF (PRG), and leukemia-associated RhoGEF (LARG)

Jaiswal, M., Gremer, L., Dvorsky, R., Haeusler, L. C., Cirstea, I. C., Uhlenbrock, K., & Ahmadian, M. R. (2011) · Journal of Biological Chemistry

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

Cited by 68

Intrinsic Disorder of the Neuronal SNARE Protein SNAP25a in its Pre-fusion Conformation

Stief, T., Gremer, L., Pribicevic, S., Espinueva, D. F., Vormann, K., Biehl, R., Jahn, R., Pérez-Lara, Á., & Lakomek, N.-A. (2023) · Journal of Molecular Biology

Cellular transport and secretionProtein Structure and Dynamics

Cited by 6